Multidrug resistance (MDR) and collateral sensitivity in bacteria, with special attention to genetic and evolutionary aspects and to the perspectives of antimicrobial …

A Fodor, BA Abate, P Deák, L Fodor, E Gyenge… - Pathogens, 2020 - mdpi.com
Antibiotic poly-resistance (multidrug-, extreme-, and pan-drug resistance) is controlled by
adaptive evolution. Darwinian and Lamarckian interpretations of resistance evolution are …

[PDF][PDF] Barriers to genetic manipulation of Enterococci: Current approaches and future directions

AL Krause, TP Stinear, IR Monk - FEMS Microbiology Reviews, 2022 - academic.oup.com
Enterococcus faecalis and Enterococcus faecium are Gram-positive commensal gut bacteria
that can also cause fatal infections. To study clinically relevant multi-drug resistant E …

A proteolytic complex targets multiple cell wall hydrolases in Pseudomonas aeruginosa

D Srivastava, J Seo, B Rimal, SJ Kim, S Zhen… - MBio, 2018 - Am Soc Microbiol
Carboxy-terminal processing proteases (CTPs) occur in all three domains of life. In bacteria,
some of them have been associated with virulence. However, the precise roles of bacterial …

The effects of daptomycin on cell wall biosynthesis in Enterococcal faecalis

B Rimal, J Chang, C Liu, R Rashid, M Singh, SJ Kim - Scientific Reports, 2023 - nature.com
Daptomycin is a cyclic lipodepsipeptide antibiotic reserved for the treatment of serious
infections by multidrug-resistant Gram-positive pathogens. Its mode of action is considered …

Mechanistic insights into the activities of major families of enzymes in bacterial peptidoglycan assembly and breakdown

JMC Kwan, Y Qiao - ChemBioChem, 2023 - Wiley Online Library
Serving as an exoskeletal scaffold, peptidoglycan is a polymeric macromolecule that is
essential and conserved across all bacteria, yet is absent in mammalian cells; this has made …

Peptidoglycan Compositional Analysis of Enterococcus faecalis Biofilm by Stable Isotope Labeling by Amino Acids in a Bacterial Culture

JD Chang, AG Wallace, EE Foster, SJ Kim - Biochemistry, 2018 - ACS Publications
Peptidoglycan (PG) is a major component of the cell wall in Enterococcus faecalis. Accurate
analysis of PG composition provides crucial insights into the bacterium's cellular functions …

[HTML][HTML] Surface proteins and the formation of biofilms by Staphylococcus aureus

SJ Kim, J Chang, B Rimal, H Yang… - Biochimica et Biophysica …, 2018 - Elsevier
Staphylococcus aureus biofilms pose a serious clinical threat as reservoirs for persistent
infections. Despite this clinical significance, the composition and mechanism of formation of …

Neuroprotection of rhubarb extract against cerebral ischaemia-reperfusion injury via the gut-brain axis pathway

M Mao, X Cao, Y Liang, Q Li, S Chen, L Zhou, Y Zhang… - Phytomedicine, 2024 - Elsevier
Background The gut-brain axis (GBA) plays a central role in cerebral ischaemia-reperfusion
injury (CIRI). Rhubarb, known for its purgative properties, has demonstrated protective …

[PDF][PDF] The growth and biofilm formation of Enterococcus faecalis in ethanol extract of Citrus aurantiifolia Indonesian species

C Soraya, Z Mubarak, BA Gani - Journal of Pharmacy & …, 2020 - researchgate.net
Abstract Resumen Context: Enterococcus faecalis is reported as a biofilm bacterium
involved in the pathogenesis of tooth root canal infection. The ability to grow and form …

Resuscitation-promoting factors are required for Mycobacterium smegmatis biofilm formation

C Ealand, B Rimal, J Chang, L Mashigo… - Applied and …, 2018 - Am Soc Microbiol
Resuscitation-promoting factors (Rpfs) have previously been shown to act as growth-
stimulatory molecules via their lysozyme-like activity on peptidoglycan in the bacterial cell …