Heterologous Prime-Boost Immunization Strategies Using Varicella-Zoster Virus gE mRNA Vaccine and Adjuvanted Protein Subunit Vaccine Triggered Superior Cell …

D Li, L Bian, L Cui, J Zhou, G Li, X Zhao… - International Journal …, 2024 - Taylor & Francis
Purpose Heterologous immunization using different vaccine platforms has been
demonstrated as an efficient strategy to enhance antigen-specific immune responses. In this …

Regulated microbe vaccines: from concept to (pre-clinical) reduction to practice

R Voellmy, DC Bloom, N Vilaboa - Expert Review of Vaccines, 2025 - Taylor & Francis
Introduction Vaccines to prevent important infections involving, eg influenza viruses, severe
acute respiratory syndrome-causing coronaviruses (eg SARS-CoV-2), respiratory syncytial …

Immunogenicity of novel live vaccine based on an artificial rHN20 strain against emerging fowl adenovirus 4

Y Zhang, Q Pan, R Guo, A Liu, Z Xu, Y Gao, H Cui… - Viruses, 2021 - mdpi.com
In recent years, hepatitis-hydropericardium syndrome (HHS), caused by novel fowl
adenovirus 4 (FAdV-4), has caused serious economic losses to the poultry industry …

Capturing structural variants of herpes simplex virus genome in full length by Oxford nanopore sequencing

R Saranathan, E Asare, L Leung… - Microbiology …, 2022 - Am Soc Microbiol
Genome sequencing and assembly of viral genomes within the Herpesviridae family,
particularly herpes simplex virus (HSV), have been challenging due to the large size (~ 154 …

[HTML][HTML] SARS-CoV-2 infection prior to vaccination amplifies Fc-mediated humoral profiles in an age-dependent manner

W Jung, A Abdelnour, P Kaplonek, R Herrero, JSL Lee… - Cell Reports, 2024 - cell.com
Immunity acquired by vaccination following infection, termed hybrid immunity, has been
shown to confer enhanced protection against severe acute respiratory syndrome …

A broad influenza vaccine based on a heat-activated, tissue-restricted replication-competent herpesvirus

N Vilaboa, DC Bloom, W Canty, R Voellmy - Vaccines, 2024 - mdpi.com
Vaccination with transiently activated replication-competent controlled herpesviruses
(RCCVs) expressing influenza A virus hemagglutinins broadly protects mice against lethal …

A Chymotrypsin-Dependent Live-Attenuated Influenza Vaccine Provides Protective Immunity against Homologous and Heterologous Viruses

P He, M Gui, T Chen, Y Zeng, C Chen, Z Lu, N Xia… - Vaccines, 2024 - mdpi.com
Influenza virus is one of the main pathogens causing respiratory diseases in humans.
Vaccines are the most effective ways to prevent viral diseases. However, the limited …

Very Broadly Effective Hemagglutinin-Directed Influenza Vaccines with Anti-Herpetic Activity

DC Bloom, C Lilly, W Canty, N Vilaboa, R Voellmy - Vaccines, 2024 - mdpi.com
A universal vaccine that generally prevents influenza virus infection and/or illness remains
elusive. We have been exploring a novel approach to vaccination involving replication …

[HTML][HTML] Recombinant Hemagglutinin Protein from H9N2 Avian Influenza Virus Exerts Good Immune Effects in Mice

X Li, Z Xie, Y Wei, M Li, M Zhang, S Luo, L Xie - Microorganisms, 2024 - mdpi.com
The H9N2 subtype of avian influenza virus (AIV) causes enormous economic losses and
poses a significant threat to public health; the development of vaccines against avian …

[引用][C] 病毒载体疫苗研究进展

王步森, 徐婧含, 高智强, 侯利华 - 合成生物学, 2024