Early programming of reproductive health and fertility: novel neuroendocrine mechanisms and implications in reproductive medicine

MA Sánchez-Garrido, D García-Galiano… - Human …, 2022 - academic.oup.com
BACKGROUND According to the Developmental Origins of Health and Disease (DOHaD)
hypothesis, environmental changes taking place during early maturational periods may alter …

Environmental epigenetics in zebrafish

V Cavalieri, G Spinelli - Epigenetics & chromatin, 2017 - Springer
It is widely accepted that the epigenome can act as the link between environmental cues,
both external and internal, to the organism and phenotype by converting the environmental …

Prenatal androgen excess induces multigenerational effects on female and male descendants

GA Abruzzese, SR Ferreira, MJ Ferrer… - Clinical Medicine …, 2023 - journals.sagepub.com
Background: It is still unelucidated how hormonal alterations affect developing organisms
and their descendants. Particularly, the effects of androgen levels are of clinical relevance …

Assessing the burden of illness associated with acquired generalized hypoactive sexual desire disorder

JA Simon, A Athavale, R Ravindranath… - Journal of Women's …, 2022 - liebertpub.com
Background: Hypoactive sexual desire disorder (HSDD), which affects∼ 10% of women in
the United States, is defined as the persistent or recurrent deficiency/absence of sexual …

[HTML][HTML] Trace elements alone or in mixtures associated with unconventional natural gas exploitation affect rat fetal steroidogenesis and testicular development in vitro.

G Baalbaki, V Lim, AP Gillet, MA Verner… - Environmental …, 2024 - Elsevier
Biomonitoring studies have shown that pregnant women living in regions of unconventional
natural gas (UNG) exploitation have higher levels of trace elements. Whether developmental …

Ameliorative effect of avocado oil against lufenuron induced testicular damage and infertility in male rats

H Ali Abd El‐Rahman, AR Omar - Andrologia, 2022 - Wiley Online Library
Lufenuron is a benzoylurea pesticide that causes significant histological and histochemical
damage in mammals. Avocado is a common food in the human diet that contains antioxidant …

Steroid hormone signaling: multifaceted support of testicular function

S Matsuyama, T DeFalco - Frontiers in Cell and Developmental …, 2024 - frontiersin.org
Embryonic development and adult physiology are dependent on the action of steroid
hormones. In particular, the reproductive system is reliant on hormonal signaling to promote …

Undernutrition and hyperandrogenism during pregnancy: Role in programming of cardiovascular disease and infertility

F Mossa, KE Latham, JJ Ireland… - Molecular …, 2019 - Wiley Online Library
Maternal nutritional status programs the development of several systems in female offspring,
with effects that depend on the severity, duration, and window of development when the …

Early prenatal androgen exposure reduces testes size and sperm concentration in sheep without altering neuroendocrine differentiation and masculine sexual …

CM Scully, CT Estill, R Amodei, A McKune… - Domestic animal …, 2018 - Elsevier
Prenatal androgens are largely responsible for growth and differentiation of the genital tract
and testis and for organization of the control mechanisms regulating male reproductive …

Delay in puberty indices of Wistar rats caused by cadmium. Focus on the redox system in reproductive organs

J Hernández-Rodríguez, AL López, S Montes… - Reproductive …, 2021 - Elsevier
Puberty is a transitional period from juvenile stage to adulthood, followed by the functional
maturation of gonads and reproductive organs. This period is sensitive to environmental …