Cells succumbing to stress via regulated cell death (RCD) can initiate an adaptive immune
response associated with immunological memory, provided they display sufficient …

Kidney stones (also known as urinary stones or nephrolithiasis) are highly prevalent,
affecting approximately 10% of adults worldwide, and the incidence of stone disease is …

In healthy individuals, the intestinal microbiota cannot access the liver, spleen, or other
peripheral tissues. Some pathogenic bacteria can reach these sites, however, and can …

The production of various reactive oxidant species in excess of endogenous antioxidant
defense mechanisms promotes the development of a state of oxidative stress, with …

Inflammaging refers to a low-grade pro-inflammatory phenotype which accompanies aging
in mammals. The aging process is associated with a decline in autophagic capacity which …

The nucleotide-binding oligomerization domain–like receptor (Nlrp) 6 maintains gut
microbiota homeostasis and regulates antibacterial immunity. We now report a role for Nlrp6 …

Increasing incidences of obesity and diabetes have made diabetic kidney disease (DKD) the
leading cause of chronic kidney disease and end-stage renal disease worldwide. Despite …

In addition to respiratory complications produced by SARS‐CoV‐2, accumulating evidence
suggests that some neurological symptoms are associated with the disease caused by this …

Inflammation is an innate immune response to infection or tissue damage that is designed to
limit harm to the host, but contributes significantly to ischemic brain injury following stroke …

Dietary salt reduction and exercise are lifestyle modifications for salt-sensitive
hypertensives. While exercise has prominent metabolic effects, salt has an adverse effect on …