Primary hepatocellular carcinoma (HCC) is one of the most fatal cancers in humans with
rising incidence in many regions around the world. Currently, no satisfactory curative …

Breast carcinogenesis and/or cancer growth and/or drug sensitivity has a multifactorial
etiology—perhaps the least well-characterized aspect being that of the distant …

Purpose: Efforts have been devoted to select eligible candidates for PD-1/PD-L1 immune
checkpoint blocker (ICB) immunotherapy. Here, we have a serendipitous finding of positron …

The facilitative glucose transporter Glut-1 is overexpressed and confers poor prognosis in a
wide range of solid tumours. The peri-necrotic pattern of expression often seen in human …

Breast cancer remains a major cause of cancer death in women in the United States. Novel
therapies are needed for patients when standard treatments are ineffective. We have …

We performed a computational study of positron attachment to hydrated amino acids,
namely glycine, alanine, and proline in the zwitterionic form. We combined the sequential …

Application of the nuclear approach for the detection of inherited diseases is an important
goal for nuclear medicine and will likely result in an important breakthrough, which will …

Cancer therapeutic methods comprising chemotherapy, radiotherapy, and surgery are so
routine in cancer treatment. Remarkably, there are several personal features which affect the …

18F-2-deoxy-2-fluoro-d-glucose (18F-FDG, later referred to as 19FDG) has been extensively
used in diagnostic positron emission tomography (PET) in oncology for many years. FDG is …

Abstract 2DG causes cytotoxicity in cancer cells by disrupting thiol metabolism while
Doxorubicin (DOX) induces cytotoxicity in tumor cells by generating reactive oxygen species …