The present invention relates to pyrrolopyrazines compounds useful as inhibitors of ATR
protein kinase. The invention also relates to pharmaceutically acceptable compositions com …

The present invention relates to compounds useful as inhibi (51) Int. Cl. tors of ATR protein
kinase. The invention also relates to CO7D 40/12(2006.01) pharmaceutically acceptable …

The invention relates to methods and compositions for the treatment or prevention of
diseases and disorders associated with myeloproliferative disorders. In particular, the …

2010-04-06 Assigned to VERTEX PHARMACEUTICALS INCORPORATED reassignment
VERTEX PHARMACEUTICALS INCORPORATED ASSIGNMENT OF ASSIGNORS …

The present invention provides for the treatment or prevention of Hepadnaviridae infection
and disease caused by Hepadnaviridae infection. In particular, the invention provides …

US8993808B2 - Phenylcyclopropylamine derivatives and their medical use - Google
Patents US8993808B2 - Phenylcyclopropylamine derivatives and their medical use …

2015-09-14 Assigned to VERTEX PHARMACEUTICALS (EUROPE) LIMITED reassignment
VERTEX PHARMACEUTICALS (EUROPE) LIMITED ASSIGNMENT OF ASSIGNORS …

The invention relates to a compound of Formula (I):(A)-(A)-(B)-(Z)-(L)-(D), wherein:(A) is
heteroaryl or aryl; each (A'), if present, is independently chosen from aryl, aryla lkoxy …

Int. C. C07D 285/12 C07D 27L/12 CO7D 263/02 C07D 275/02 CO7D 26/02 CO7D 239/42
A6 IK3I/433 A6 IK3I/4245 A6 IK3I/422 C07D 213/73 C07D 237/20 CO7D 24/20 C07D …

2011-10-13 Assigned to VERTEX PHARMACEUTICALS INCORPORATED reassignment
VERTEX PHARMACEUTICALS INCORPORATED ASSIGNMENT OF ASSIGNORS …