The surface of the protozoan parasite Trypanosoma cruzi is covered in mucins, which
contribute to parasite protection and to the establishment of a persistent infection. Their …

Trypanosoma cruzi, Trypanosoma brucei and Leishmania (Trypanosomatidae:
Kinetoplastida) are parasitic protozoan causing Chagas disease, African Trypanosomiasis …

Whole-genome sequencing of the protozoan pathogen Trypanosoma cruzi revealed that the
diploid genome contains a predicted 22,570 proteins encoded by genes, of which 12,570 …

Trypanosomes are eukaryotic, unicellular parasites, such as Trypanosoma brucei, which
causes sleeping sickness, and Trypanosoma cruzi, which causes Chagas disease …

Although the genome of Trypanosoma cruzi, the causative agent of Chagas disease, was
first made available in 2005, with additional strains reported later, the intrinsic genome …

Chagas disease, caused by the protozoan Trypanosoma cruzi, is a lifelong and debilitating
illness of major significance throughout Latin America and an emergent threat to global …

Chagas disease caused by the parasite Trypanosoma cruzi affects millions of people.
Although its first genome dates from 2005, its complexity hindered a complete assembly and …

Trypanosoma cruzi (T. cruzi) is the causative agent for Chagas disease (CD). There is a
critical lack of methods for prevention of infection or treatment of acute infection and chronic …

Introduction Chagas disease (CD) affects~ 7 million people worldwide. Benznidazole (BZN)
and nifurtimox (NFX) are the only approved drugs for CD chemotherapy. Although both …

Parasites are responsible for the most neglected tropical diseases, affecting over a billion
people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible …