i-Motif DNA: structure, stability and targeting with ligands
HA Day, P Pavlou, ZAE Waller - Bioorganic & medicinal chemistry, 2014 - Elsevier
Abstract i-Motifs are four-stranded DNA secondary structures which can form in sequences
rich in cytosine. Stabilised by acidic conditions, they are comprised of two parallel-stranded …
rich in cytosine. Stabilised by acidic conditions, they are comprised of two parallel-stranded …
Microsatellites: genomic distribution, putative functions and mutational mechanisms: a review
Microsatellites, or tandem simple sequence repeats (SSR), are abundant across genomes
and show high levels of polymorphism. SSR genetic and evolutionary mechanisms remain …
and show high levels of polymorphism. SSR genetic and evolutionary mechanisms remain …
DNA: structure and function
RR Sinden, CE Pearson, VN Potaman… - Advances in genome …, 1998 - Elsevier
Publisher Summary This chapter discusses the structure and function of DNA. DNA occupies
a critical role in cells, because it is the source of all intrinsic genetic information. Chemically …
a critical role in cells, because it is the source of all intrinsic genetic information. Chemically …
G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription
S Cogoi, LE Xodo - Nucleic acids research, 2006 - academic.oup.com
In human and mouse, the promoter of the KRAS gene contains a nuclease hypersensitive
polypurine–polypyrimidine element (NHPPE) that is essential for transcription. An interesting …
polypurine–polypyrimidine element (NHPPE) that is essential for transcription. An interesting …
Triplex DNA structures
MD Frank-Kamenetskii, SM Mirkin - Annual review of …, 1995 - annualreviews.org
A DNA triplex is formed when pyrimidine or purine bases occupy the major groove of the
DNA double Helix forming Hoogsteen pairs with purines of the Watson-Crick basepairs …
DNA double Helix forming Hoogsteen pairs with purines of the Watson-Crick basepairs …
Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions
Y Qin, LH Hurley - Biochimie, 2008 - Elsevier
In its simplest form, a DNA G-quadruplex is a four-stranded DNA structure that is composed
of stacked guanine tetrads. G-quadruplex-forming sequences have been identified in …
of stacked guanine tetrads. G-quadruplex-forming sequences have been identified in …
Simple sequence repeats as a source of quantitative genetic variation
Y Kashi, D King, M Soller - Trends in genetics, 1997 - cell.com
Most traits in biological populations appear to be under stabilizing selection, which acts to
eliminate quantitative genetic variation. Yet, virtually all measured traits in biological …
eliminate quantitative genetic variation. Yet, virtually all measured traits in biological …
Characterization and identification of microRNA core promoters in four model species
MicroRNAs are short, noncoding RNAs that play important roles in post-transcriptional gene
regulation. Although many functions of microRNAs in plants and animals have been …
regulation. Although many functions of microRNAs in plants and animals have been …
Heterogeneous nuclear ribonucleoprotein K is a transcription factor
EF Michelotti, GA Michelotti, AI Aronsohn… - Molecular and cellular …, 1996 - Taylor & Francis
The CT element is a positively acting homopyrimidine tract upstream of the c-myc gene to
which the well-characterized transcription factor Sp1 and heterogeneous nuclear …
which the well-characterized transcription factor Sp1 and heterogeneous nuclear …
[PDF][PDF] H-DNA and related structures
SM Mirkin, MD Frank-Kamenetskii - Annual review of biophysics …, 1994 - researchgate.net
542 MIRKIN & FRANK-KAMENETSKII and cruciform formation in supercoiled plasmids (71,
97, 116) stimulated interest in unusual DNA conformations and their possible biological role …
97, 116) stimulated interest in unusual DNA conformations and their possible biological role …