Colorectal cancer in Saudi Arabia as the proof-of-principle model for implementing strategies of predictive, preventive, and personalized medicine in healthcare

M Alyabsi, A Alhumaid, H Allah-Bakhsh, M Alkelya… - EPMA Journal, 2020 - Springer
Colorectal cancer (CRC) is the most commonly diagnosed cancer among Saudi males and
ranks third in females with up to 73% of cases diagnosed at late stage. This review provides …

[HTML][HTML] Support vector machine classifier for prediction of the metastasis of colorectal cancer

J Zhi, J Sun, Z Wang, W Ding - … journal of molecular …, 2018 - spandidos-publications.com
Colorectal cancer (CRC) is one of the most common cancers and a major cause of mortality.
The present study aimed to identify potential biomarkers for CRC metastasis and uncover …

Colorectal cancer prediction based on weighted gene co-expression network analysis and variational auto-encoder

D Ai, Y Wang, X Li, H Pan - Biomolecules, 2020 - mdpi.com
An effective feature extraction method is key to improving the accuracy of a prediction model.
From the Gene Expression Omnibus (GEO) database, which includes 13,487 genes, we …

[HTML][HTML] Identification of potential biomarkers with colorectal cancer based on bioinformatics analysis and machine learning

A Hammad, M Elshaer, X Tang - Mathematical Biosciences and …, 2021 - aimspress.com
Colorectal cancer (CRC) is one of the most common malignancies worldwide. Biomarker
discovery is critical to improve CRC diagnosis, however, machine learning offers a new …

Plasma metabolomics, lipidomics and cytokinomics profiling predict disease recurrence in metastatic colorectal cancer patients undergoing liver resection

S Costantini, E Di Gennaro, F Capone… - Frontiers in …, 2023 - frontiersin.org
Purpose In metastatic colorectal cancer (mCRC) patients (pts), treatment strategies
integrating liver resection with induction chemotherapy offer better 5-year survival rates than …

A novel method detecting the key clinic factors of portal vein system thrombosis of splenectomy & cardia devascularization patients for cirrhosis & portal hypertension

M Wang, L Ding, M Xu, J Xie, S Wu, S Xu, Y Yao… - BMC …, 2019 - Springer
Background Portal vein system thrombosis (PVST) is potentially fatal for patients if the
diagnosis is not timely or the treatment is not proper. There hasn't been any available …

Distinguishing rectal cancer from colon cancer based on the support vector machine method and RNA-sequencing data

Y Zhang, Y Wu, Z Gong, H Ye, X Zhao, J Li… - Current medical …, 2021 - Springer
Colorectal cancer (CRC) is the third most commonly diagnosed cancer worldwide. Several
studies have indicated that rectal cancer is significantly different from colon cancer in terms …

[PDF][PDF] Gly-LysPred: identification of lysine glycation sites in protein using position relative features and statistical moments via Chou's 5 step rule

S Khanum, MA Ashraf, A Karim, B Shoaib… - … and Continua (CMC …, 2020 - researchgate.net
Glycation is a non-enzymatic post-translational modification which assigns sugar molecule
and residues to a peptide. It is a clinically important attribute to numerous age-related …

Identification of diagnostic biomarker in patients with gestational diabetes mellitus based on transcriptome‐wide gene expression and pattern recognition

Y Wang, Z Wang, H Zhang - Journal of Cellular Biochemistry, 2019 - Wiley Online Library
Gestational diabetes mellitus (GDM) is becoming a growing threat for all pregnancies. In this
study, we set up an automatic screening method combining both transcriptomic databases …

P-cadherin regulates intestinal epithelial cell migration and mucosal repair, but is dispensable for colitis associated colon cancer

NG Naydenov, S Lechuga, A Zalavadia, PK Mukherjee… - Cells, 2022 - mdpi.com
Recurrent chronic mucosal inflammation, a characteristic of inflammatory bowel diseases
(IBD), perturbs the intestinal epithelial homeostasis resulting in formation of mucosal …