Abstract Calcium (Ca 2+) and reactive oxygen species (ROS) are versatile signaling
molecules coordinating physiological and pathophysiological processes. While channels …

The mitochondria are double-membrane organelles integral for energy metabolism.
Mitochondrial dynamics is regulated by inner and outer mitochondrial membrane (IMM and …

The emerging role of mitochondria as signaling organelles raises the question of whether
individual mitochondria can initiate heterotypic communication with neighboring organelles …

Mitochondria, widely known as the energy factories of eukaryotic cells, have a myriad of vital
functions across diverse cellular processes. Dysfunctions within mitochondria serve as …

Cisplatin (DDP) is the first-line chemotherapeutic agent for ovarian cancer. However, the
development of DDP resistance seriously influences the chemotherapeutic effect and …

HIV-associated neurological dysfunction is observed in more than half of the HIV-infected
population, even in the current antiretroviral era. The mechanisms by which HIV mediates …

Cancer represents a leading cause of death worldwide. Hence, a better understanding of
the molecular mechanisms causing and propelling the disease is of utmost importance …

Cellular homeostasis requires critical communications between the endoplasmic reticulum
(ER) and mitochondria to maintain the viability of cells. This communication is mediated and …

Epimedokoreanin B (EKB) is a prenylated flavonoid isolated from Epimedium koreanum. In
this article, we described the anti-cancerous effects of EKB and its underlying mechanism in …

Objective The mitochondrial phenotype, governed by the balance of fusion-fission, is a key
determinant of energy metabolism. The inner and outer mitochondrial membrane (IMM) …