Cattle are able to produce a full range of Ig classes including the long-elusive IgD through
rearrangement of their germline genes. Several IgL groupings have been reported but as in …

Theileria parasites are classified in the phylum Apicomplexa that includes several genera of
medical and veterinary importance such as Plasmodium, Babesia, Toxoplasma and …

Infectious agents develop intricate mechanisms to interact with host cell pathways and hijack
their genetic and epigenetic machinery to change host cell phenotypic states. Among the …

The CD5 lymphocyte surface receptor is a group B member of the ancient and highly
conserved scavenger receptor cysteine-rich superfamily. CD5 is expressed on mature T and …

Theileria parasites invade and transform bovine leukocytes causing either East Coast fever
(T. parva), or tropical theileriosis (T. annulata). Susceptible animals usually die within weeks …

Theileria parasites infect and transform bovine lymphocytes resulting in tumors with
metastatic/invasive potential. Importantly, cellular transformation is reversed upon drug …

The intracellular parasite Theileria is the only eukaryote known to transform its mammalian
host cells. We investigated the host mechanisms involved in parasite-induced transformation …

CD5 and CD6 are closely related signal-transducing class I scavenger receptors mainly
expressed on lymphocytes. Both receptors are involved in the modulation of the activation …

Theileria parasites infect and transform bovine lymphocytes, but host cell immortalization is
reversible, as upon parasite death the lymphocytes rapidly die of apoptosis. Infection leads …

This study was carried out to investigate fifteen cases of acute lethal infection of calves (≤ 4
months of age) by the protozoan parasite Theileria (T.) annulata in the south of Portugal …