As life expectancy continues to increase worldwide, age-related dysfunction will largely
impact our societies in the future. Aging is well established to promote the deterioration of …

The hippocampus (HPC) and medial prefrontal cortex (mPFC) have well-established roles in
cognition, emotion, and sensory processing. In recent years, interests have shifted towards …

Cognitive processes involve precisely coordinated neuronal communications between
multiple cerebral cortical structures in a task specific manner. Rich new evidence now …

Central nervous system myelination increases action potential conduction velocity.
However, it is unclear how myelination is coordinated to ensure the temporally precise …

Therapeutic interventions have not yet been shown to demonstrate restorative effects for
declining long-term memory (LTM) that affects many healthy older adults. We developed a …

Humans are adept in simultaneously following multiple goals, but the neural mechanisms for
maintaining specific goals and distinguishing them from other goals are incompletely …

Meta-analysis of genome-wide association study data has implicated PDE4B in the
pathogenesis of Alzheimer's disease (AD), the leading cause of senile dementia. PDE4B …

Background Prenatal alcohol exposure (PAE) is a significant risk factor for developmental
disability, although its health consequences across the lifespan are poorly understood …

Normal aging is typically associated with declines in navigation and spatial memory abilities.
However, increased interindividual variability in performance across various …

Cannabidiol (CBD) is a non-intoxicating phytocannabinoid whose purported therapeutic
benefits and impression of a high safety profile has promoted its increasing popularity …