Polypropylene pelvic mesh: What went wrong and what will be of the future?

A Seifalian, Z Basma, A Digesu, V Khullar - Biomedicines, 2023 - mdpi.com
Background: Polypropylene (PP) pelvic mesh is a synthetic mesh made of PP polymer used
to treat pelvic organ prolapse (POP). Its use has become highly controversial due to reports …

Functionalized strategies and mechanisms of the emerging mesh for abdominal wall repair and regeneration

Z Liu, N Wei, R Tang - ACS Biomaterials Science & Engineering, 2021 - ACS Publications
Meshes have been the overwhelmingly popular choice for the repair of abdominal wall
defects to retrieve the bodily integrity of musculofascial layer. Broadly, they are classified into …

Functional supramolecular bioactivated electrospun mesh improves tissue ingrowth in experimental abdominal wall reconstruction in rats

MGMCM da Cunha, B Arts, L Hympanova, R Rynkevic… - Acta biomaterialia, 2020 - Elsevier
Abstract Development of biomaterials for hernia and pelvic organ prolapse (POP) repair is
encouraged because of high local complication rates with current materials. Therefore, we …

Electrospun nanofiber mesh with fibroblast growth factor and stem cells for pelvic floor repair

SG Hansen, MB Taskin, M Chen… - … Research Part B …, 2020 - Wiley Online Library
Surgical outcome following pelvic organ prolapse (POP) repair needs improvement. We
suggest a new approach based on a tissue‐engineering strategy. In vivo, the regenerative …

Absorbable electrospun poly-4-hydroxybutyrate scaffolds as a potential solution for pelvic organ prolapse surgery

K Verhorstert, A Gudde, C Weitsz… - ACS Applied Bio …, 2022 - ACS Publications
Women with pelvic organ prolapse (POP) have bothersome complaints that significantly
affect their quality of life. While native tissue repair is associated with high recurrence rates …

The use of polymeric meshes for pelvic organ prolapse: Current concepts, challenges, and future perspectives

E Mancuso, C Downey, E Doxford‐Hook… - … Research Part B …, 2020 - Wiley Online Library
Pelvic organ prolapse (POP) is one of the most common chronic disorders in women,
impacting the quality of life of millions of them worldwide. More than 100 surgical procedures …

The effect of growth factors on vaginal wound healing: a systematic review and meta-analysis

MJJ van Velthoven, AN Gudde, F Struijs… - … Engineering Part B …, 2023 - liebertpub.com
Surgical outcomes of pelvic organ prolapse (POP) surgery are poor, resulting in a 20%
recurrence risk. Following the hypothesis that impaired wound healing is the main …

Ibuprofen‐loaded bilayer electrospun mesh modulates host response toward promoting full‐thickness abdominal wall defect repair

J Liu, R Tang, X Zhu, Q Ma, X Mo… - Journal of Biomedical …, 2024 - Wiley Online Library
Pro‐inflammatory response impairs the constructive repair of abdominal wall defects after
mesh implantation. Electrospinning‐aid functionalization has the potential to improve the …

Current practice in animal models for pelvic floor dysfunction

F Fang, Z Zhao, J Xiao, J Wen, J Wu, Y Miao - International Urogynecology …, 2023 - Springer
Introduction and hypothesis The objective was to explore the current practice of using
animal models for female pelvic floor dysfunction (PFD). Methods By applying PFD and …

In vitro simulation of in vivo degradation and cyclic loading of novel degradable electrospun meshes for prolapse repair

R Rynkevic, P Martins, A Fernandes, J Vange… - Polymer Testing, 2019 - Elsevier
Synthetic durable textile meshes used in pelvic organ prolapse (POP) may lead to graft
related complications (GRCs). Mechanisms involved in the genesis of GRCs include implant …