[HTML][HTML] Targeting of GSDMD sensitizes HCC to anti-PD-1 by activating cGAS pathway and downregulating PD-L1 expression
T Lv, X Xiong, W Yan, M Liu, H Xu… - … for Immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Background Gasdermin D (GSDMD) is well known as a downstream of inflammasomes.
However, the roles of GSDMD itself in hepatocellular carcinoma (HCC) remain unclear …
However, the roles of GSDMD itself in hepatocellular carcinoma (HCC) remain unclear …
Leishmania surface molecule lipophosphoglycan‐TLR2 interaction moderates TPL2‐mediated TLR2 signalling for parasite survival
SK Ghosh, D Shukla, H Mahor, SK Srivastava… - …, 2024 - Wiley Online Library
Leishmania donovani, a protozoan parasite, resides and replicates in macrophages and
inflicts the potentially fatal disease visceral leishmaniasis (VL). The parasite‐expressed …
inflicts the potentially fatal disease visceral leishmaniasis (VL). The parasite‐expressed …
Identification of the association between toll-like receptors and T-cell activation in Takayasu's arteritis
Y Tian, B Huang, J Li, X Tian, X Zeng - Frontiers in Immunology, 2022 - frontiersin.org
To explore the relationships between Toll-like receptors (TLRs) and the activation and
differentiation of T-cells in Takayasu's arteritis (TAK), using real-time fluorescence …
differentiation of T-cells in Takayasu's arteritis (TAK), using real-time fluorescence …
Anti-Leishmania major Properties of Nuphar lutea (Yellow Water Lily) Leaf Extracts and Purified 6,6′ Dihydroxythiobinupharidine (DTBN)
O Shmuel, A Rasti, M Zaknoun, N Astman… - Pathogens, 2024 - mdpi.com
Cutaneous leishmaniasis (CL) is a zoonotic disease, manifested as chronic ulcers,
potentially leaving unattractive scars. There is no preventive vaccination or optimal …
potentially leaving unattractive scars. There is no preventive vaccination or optimal …
Myotubularin-related protein-6 silencing protects mice from Leishmania donovani infection
The protozoan parasite Leishmania donovani resides within mammalian macrophages and
alters its antigen-presenting functions to negatively regulate host-protective T cell …
alters its antigen-presenting functions to negatively regulate host-protective T cell …
Myotubularin-related protein 6 is an ion channel-associated pro-leishmanial phosphatase
S Parveen, S Majumder, N Bodhale, NR Biswal… - International …, 2024 - Elsevier
Residing obligatorily as amastigotes within the mammalian macrophages, the parasite
Leishmania donovani inflicts the potentially fatal, globally re-emerging disease visceral …
Leishmania donovani inflicts the potentially fatal, globally re-emerging disease visceral …
Mono‐palmitoyl‐N‐alkylurea ligands as specific activators of human Toll‐like receptor 2/6 heterodimer
MME Isendoorn, G Castello, Ç Koç, N Meeuwenoord… - ChemBioChem - Wiley Online Library
Ligands for Toll‐like‐receptor 2 (TLR2) have demonstrated significant potential as immune‐
stimulating components in synthetic vaccines. Activation of TLR2 relies on the formation of …
stimulating components in synthetic vaccines. Activation of TLR2 relies on the formation of …
The infiltration of monocytes aggravates liver fibrosis in mice infected with Echinococcus granulosus
Y Yan, F Tian, X Qi, Y Liu, X Ma, B Li, J Lv, X Zhou… - 2022 - researchsquare.com
Background Echinococcus granulosus (E. granulosus) infection involves multicellular
inflammatory responses and fibrous repair. The study aimed to observe the effect of …
inflammatory responses and fibrous repair. The study aimed to observe the effect of …