Telomeres, the protective structures of chromosome ends are gradually shortened by each
cell division, eventually leading to senescence or apoptosis. Cancer cells maintain the …

Telomere repeat binding factor 2 (TRF2), a critical element of the shelterin complex, plays a
vital role in the maintenance of genome integrity. TRF2 overexpression is found in a wide …

Shelterin proteins regulate genomic stability by preventing inappropriate DNA damage
responses (DDRs) at telomeres. Unprotected telomeres lead to persistent DDR causing cell …

Simple Summary Short, dysfunctional telomeres represent the genetic biomarkers of cancer.
Studies in early-stage non-small-cell lung cancer (NSCLC) have shown that telomere length …

Cervical cancer is associated with abnormal expression of multiple genes. Survivin and Bcl-
2 proteins are apoptosis inhibitors. The tumor suppressor gene CD82, which encodes the …

Background Colorectal cancer is one of most common tumors in developed countries and,
despite improvements in treatment and diagnosis, mortality rate of patients remains high …

Risk of relapse of endometrial cancer (EC) after surgical treatment is 13% and recurrent
disease carries a poor prognosis. Research into prognostic indicators is essential to improve …

Telomere repeat-binding factor 2 (TRF2) is a crucial component of the shelterin complex,
commonly overexpressed in osteosarcoma (OS) and positively correlated with its …

Background: Survivin has been shown to play an important role in cancer pathogenesis.
However, its role in cervical cancer development is still controversial. This study was …

miR-329-3p expression in cervical cancer Page 1 4045 Abstract. – OBJECTIVE: miR-329-3p
has been reported to serve as a tumor suppressor in the progression of cervical cancer (CC) …