Stress proteins: the biological functions in virus infection, present and challenges for target-based antiviral drug development

Q Wan, D Song, H Li, M He - Signal transduction and targeted therapy, 2020 - nature.com
Stress proteins (SPs) including heat-shock proteins (HSPs), RNA chaperones, and ER
associated stress proteins are molecular chaperones essential for cellular homeostasis. The …

[HTML][HTML] Molecular mechanism of hepatitis B virus-induced hepatocarcinogenesis

M Tarocchi, S Polvani, G Marroncini… - World Journal of …, 2014 - ncbi.nlm.nih.gov
Hepatitis B virus (HBV) infection is a global public health problem with approximately 2
billion people that have been exposed to the virus. HBV is a member of a family of small …

Heat shock proteins and viral infection

X Zhang, W Yu - Frontiers in immunology, 2022 - frontiersin.org
Heat shock proteins (HSPs) are a kind of proteins which mostly found in bacterial, plant and
animal cells, in which they are involved in the monitoring and regulation of cellular life …

Molecular functions and biological roles of hepatitis B virus x protein

H Tang, N Oishi, S Kaneko, S Murakami - Cancer science, 2006 - Wiley Online Library
Chronic infection of hepatitis B virus (HBV) is one of the major causes of hepatocellular
carcinoma (HCC) in the world. Hepatitis B virus X protein (HBx) has been long suspected to …

Hepatitis B virus-related hepatocellular carcinoma: paradigms for viral-related human carcinogenesis

D Kremsdorf, P Soussan, P Paterlini-Brechot… - Oncogene, 2006 - nature.com
As discussed in detail in other chapters of this review, chronic hepatitis B (HBV) infection is a
major risk factor for hepatocellular carcinoma (HCC). Most HCCs complicate the evolution of …

Effects of hepatitis B virus X protein on the development of liver cancer

X Zhang, H Zhang, L Ye - Journal of Laboratory and Clinical Medicine, 2006 - Elsevier
Hepatitis B virus (HBV) infections play an important role in the development of cirrhosis and
hepatocellular carcinoma (HCC). The pathogenesis of HBV-related HCC, however, has not …

Hepatitis B virus X gene and hepatocarcinogenesis

SA Ng, C Lee - Journal of gastroenterology, 2011 - Springer
Chronic hepatitis B virus (HBV) infection has been identified as a major risk factor in
hepatocellular carcinoma (HCC), which is one of the most common cancers worldwide. The …

Mitochondria and viruses

A Ohta, Y Nishiyama - Mitochondrion, 2011 - Elsevier
Mitochondria are involved in a variety of cellular metabolic processes, and their functions
are regulated by extrinsic and intrinsic stimuli including viruses. Recent studies have shown …

Listeria monocytogenes Uses Listeria Adhesion Protein (LAP) To Promote Bacterial Transepithelial Translocation and Induces Expression of LAP Receptor Hsp60

KM Burkholder, AK Bhunia - Infection and immunity, 2010 - Am Soc Microbiol
Listeria monocytogenes interaction with the intestinal epithelium is a key step in the infection
process. We demonstrated that Listeria adhesion protein (LAP) promotes adhesion to …

Hepatitis B virus HBx protein interactions with the ubiquitin proteasome system

MM Minor, BL Slagle - Viruses, 2014 - mdpi.com
The hepatitis B virus (HBV) causes acute and chronic hepatitis, and the latter is a major risk
factor for the development of hepatocellular carcinoma (HCC). HBV encodes a 17-kDa …