Because of the colossal global burden of diabetes, there is an urgent need for more effective
and safer drugs. We designed and synthesized a new series of aurone derivatives …

In the present study, a series of 2-amino-4, 6-diarylpyrimidine derivatives was designed,
synthesized, characterized and evaluated for their in vitro α-glucosidase and α-amylase …

Inhibition of α-amylase and α-glucosidase activity is an effective way for controlling
postprandial blood glucose-related diabetes. The study found that hesperetin-Cu (II) …

Abstract A series of 1, 2, 4-triazole Schiffs bases 3-9 and their respective acyclo
thioglycosides 10-15 based α-glucosidase and α-amylase inhibitors were synthesized under …

Herein, a library of novel pyridone derivatives 1–34 was designed, synthesized, and
evaluated for α‐amylase and α‐glucosidase inhibitory as well as antioxidant activities …

Glucose and lipid metabolism disorders are the core pathological mechanism of a variety of
metabolic diseases, and the incidence of related diseases is increasing year by year, which …

The Knoevenagel condensation is a powerful and primary step for the development of
carbon-carbon bond transformations. These condensations offer versatile …

Isoxazolidine derivatives were designed, synthesized, and characterized using different
spectroscopic techniques and elemental analysis and then evaluated for their ability to …

Background: Diabetes mellitus is a significant health disorder; therefore, researchers should
focus on discovering new drug candidates. Methods: A series of indole–pyridine carbonitrile …

Background: Diabetes mellitus is a serious global health concern, and this is expected to
impact more than 300 million people by 2025. The current study focuses on identifying …