Cancers of the gastrointestinal (GI) tract greatly contribute to the global cancer burden and
cancer-related death. Claudin-18.2 (CLDN18. 2), a transmembrane protein, is a major …

Claudins are major components of tight junctions that maintain cell polarity and intercellular
adhesion. The dynamics of claudins in cancer cells have attracted attention as a therapeutic …

Gallbladder cancer (GBC) is an aggressive neoplasm that in an early stage is generally
asymptomatic and, in most cases, is diagnosed in advanced stages with a very low life …

Mucin glycans are an important component of the mucus barrier and a vital defence against
physical and chemical damage as well as pathogens. There are 20 mucins in the human …

Cancer is one of the leading global causes of death and disease, and treatment options are
constantly evolving. In this sense, the use of monoclonal antibodies (mAbs) in …

Gastric cancer (GC) is a complex and highly variable disease, ranking among the top five
cancers diagnosed globally, and a leading cause of cancer-related deaths. Emerging from …

Gallbladder cancer (GBC) is a very aggressive malignant neoplasm of the biliary tract with a
poor prognosis. There are no specific therapies for the treatment of GBC or early diagnosis …

Objectives A classification system for endocervical adenocarcinoma (ECA) based on high‐
risk human papillomavirus (HPV) status has been established; however, the …

Simple Summary Biliary tract cancers (BTC) are tumors arising from cells lining ducts in the
liver that facilitate the transport of bile into the gastrointestinal tract. They are often divided …

Testicular germ cell tumors (TGCT) are the most common reproductive system malignancies
in men aged 15–44 years, accounting for 95% of all testicular tumors. Our previous studies …