The interferon (IFN) system is an extremely powerful antiviral response that is capable of
controlling most, if not all, virus infections in the absence of adaptive immunity. However …

Current understanding of the molecular basis of pathogenesis of foot-and-mouth disease
(FMD) has been achieved through over 100 years of study into the biology of the etiologic …

Viral reproduction is contingent on viral protein synthesis that relies on the host ribosomes.
As such, viruses have evolved remarkable strategies to hijack the host translational …

Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals.
The disease affects many areas of the world, often causing extensive epizootics in livestock …

Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals,
which has been regarded as a persistent challenge for the livestock industry in many …

The eukaryotic initiation factor eIF4G is a large modular protein which serves as a docking
site for initiation factors and proteins involved in RNA translation. Together with eIF4E and …

Internal ribosome entry site (IRES) elements were discovered in picornaviruses. These
elements are cis-acting RNA sequences that adopt diverse three-dimensional structures and …

Foot-and-mouth disease is a highly contagious viral illness of wild and domestic cloven-
hoofed animals. The causative agent, foot-and-mouth disease virus (FMDV), replicates …

Foot-and-mouth disease virus (FMDV) represses host translation machinery, blocks protein
secretion, and cleaves cellular proteins associated with signal transduction and the innate …

Field strains of Foot-and-mouth disease virus (FMDV) use a number of α v-integrins as
receptors to initiate infection on cultured cells, and integrins are believed to be the receptors …