Emerging evidence of pathological roles of very-low-density lipoprotein (VLDL)

JK Huang, HC Lee - International journal of molecular sciences, 2022 - mdpi.com
Embraced with apolipoproteins (Apo) B and Apo E, triglyceride-enriched very-low-density
lipoprotein (VLDL) is secreted by the liver into circulation, mainly during post-meal hours …

Influence of body weight on bone mass, architecture and turnover

UT Iwaniec, RT Turner - Journal of Endocrinology, 2016 - joe.bioscientifica.com
Aldosterone, secreted by the adrenal zona glomerulosa, enhances sodium retention, thus
increasing blood volume and pressure. Excessive production of aldosterone results in high …

Continuum of renin-independent aldosteronism in normotension

R Baudrand, FJ Guarda, C Fardella, G Hundemer… - …, 2017 - Am Heart Assoc
Primary aldosteronism is a severe form of autonomous aldosteronism. Milder forms of
autonomous and renin-independent aldosteronism may be common, even in normotension …

Repurposing existing drugs for COVID-19: an endocrinology perspective

FA Cadegiani - BMC endocrine disorders, 2020 - Springer
Abstract Background Coronavirus Disease 2019 (COVID-19) is a multi-systemic infection
caused by the novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), that …

Dietary sodium restriction increases the risk of misinterpreting mild cases of primary aldosteronism

R Baudrand, FJ Guarda, J Torrey… - The Journal of …, 2016 - academic.oup.com
Context: The aldosterone to renin ratio (ARR) is recommended to screen for primary
aldosteronism (PA). Objective: To evaluate whether dietary sodium restriction results in …

Renin–angiotensin system at the crossroad of hypertension and hypercholesterolemia

C Borghi, R Urso, AF Cicero - Nutrition, Metabolism and Cardiovascular …, 2017 - Elsevier
Aim The aim of this study is to discuss the reliable scientific evidence of an interactive link
between hypertension and hypercholesterolemia considering the metabolic pathways and …

Sex differences in coronary microvascular function in individuals with type 2 diabetes

AV Haas, BA Rosner, RY Kwong, AD Rao, R Garg… - Diabetes, 2019 - Am Diabetes Assoc
Cardiovascular (CV) disease fatality rates are higher for women compared with men with
diabetes despite lower rates of obstructive coronary artery disease (CAD). Impaired …

[HTML][HTML] Atorvastatin inhibits pro-inflammatory actions of aldosterone in vascular smooth muscle cells by reducing oxidative stress

T Bruder-Nascimento, GE Callera, AC Montezano… - Life sciences, 2019 - Elsevier
Vascular inflammatory responses play an important role in several cardiovascular diseases.
Of the many pro-inflammatory vasoactive factors implicated in this process, is aldosterone …

Targeting cholesterol-dependent adrenal steroidogenesis for management of primary aldosteronism

H Wu, H He, T Han, X Tian, Z Zhu - Trends in Endocrinology & Metabolism, 2025 - cell.com
Primary aldosteronism (PA) is a common, salt-sensitive form of endocrine hypertension.
Compared with essential hypertension (EH), PA is more susceptible to cardiorenal …

Effects of statins on renin–angiotensin system

N Kiaie, AM Gorabi, Ž Reiner, T Jamialahmadi… - Journal of …, 2021 - mdpi.com
Statins, a class of drugs for lowering serum LDL-cholesterol, have attracted attention
because of their wide range of pleiotropic effects. An important but often neglected effect of …