Antimicrobial resistance and virulence: a successful or deleterious association in the bacterial world?
Hosts and bacteria have coevolved over millions of years, during which pathogenic bacteria
have modified their virulence mechanisms to adapt to host defense systems. Although the …
have modified their virulence mechanisms to adapt to host defense systems. Although the …
Nucleotide, c-di-GMP, c-di-AMP, cGMP, cAMP,(p) ppGpp signaling in bacteria and implications in pathogenesis
For an organism to survive, it must be able to sense its environment and regulate
physiological processes accordingly. Understanding how bacteria integrate signals from …
physiological processes accordingly. Understanding how bacteria integrate signals from …
Temporal shifts in antibiotic resistance elements govern phage-pathogen conflicts
KN LeGault, SG Hays, A Angermeyer, AC McKitterick… - Science, 2021 - science.org
INTRODUCTION In nature, bacteria contend with abundant and diverse viruses (phages),
necessitating an extensive repertoire of defense systems. Antiphage systems cluster …
necessitating an extensive repertoire of defense systems. Antiphage systems cluster …
The hidden life of integrative and conjugative elements
Integrative and conjugative elements (ICEs) are widespread mobile DNA that transmit both
vertically, in a host-integrated state, and horizontally, through excision and transfer to new …
vertically, in a host-integrated state, and horizontally, through excision and transfer to new …
Multiple roles of c-di-GMP signaling in bacterial pathogenesis
M Valentini, A Filloux - Annual review of microbiology, 2019 - annualreviews.org
The intracellular signaling molecule cyclic di-GMP (c-di-GMP) regulates the lifestyle of
bacteria and controls many key functions and mechanisms. In the case of bacterial …
bacteria and controls many key functions and mechanisms. In the case of bacterial …
Comparative ICE genomics: insights into the evolution of the SXT/R391 family of ICEs
RAF Wozniak, DE Fouts, M Spagnoletti… - PLoS …, 2009 - journals.plos.org
Integrating and conjugative elements (ICEs) are one of the three principal types of self-
transmissible mobile genetic elements in bacteria. ICEs, like plasmids, transfer via …
transmissible mobile genetic elements in bacteria. ICEs, like plasmids, transfer via …
Insight into the effect of nitrate on AGS granulation: granular characteristics, microbial community and metabolomics response
D Wu, B Zhao, P Zhang, Q An - Water Research, 2023 - Elsevier
As a promising wastewater treatment technology, aerobic granular sludge (AGS) process is
still hindered by slow granule formation and easy disintegration in the application. While …
still hindered by slow granule formation and easy disintegration in the application. While …
c-di-GMP Turn-Over in Clostridium difficile Is Controlled by a Plethora of Diguanylate Cyclases and Phosphodiesterases
Clostridium difficile infections have become a major healthcare concern in the last decade
during which the emergence of new strains has underscored this bacterium's capacity to …
during which the emergence of new strains has underscored this bacterium's capacity to …
Genomics and the evolution of antibiotic resistance
Antibiotic resistance arises as a consequence of complex interactions among genes, mobile
elements, and their bacterial hosts, coupled with the intense selection pressures imposed by …
elements, and their bacterial hosts, coupled with the intense selection pressures imposed by …
Acquisition and evolution of SXT-R391 integrative conjugative elements in the seventh-pandemic Vibrio cholerae lineage
ABSTRACT SXT-R391 Integrative conjugative elements (ICEs) are self-transmissible mobile
genetic elements able to confer multidrug resistance and other adaptive features to bacterial …
genetic elements able to confer multidrug resistance and other adaptive features to bacterial …