Platelets are increasingly being recognized for playing roles beyond thrombosis and
hemostasis. Today we know that they mediate inflammation by direct interactions with innate …

Chitin, a natural polymer of N-acetylglucosamine chains, is a principal component of the
apical extracellular matrix in arthropods. Chitin microfibrils serve as structural components of …

Background: Venous thromboembolism (VTE) is a life-threatening vascular event with
environmental and genetic determinants. Recent VTE genome-wide association studies …

Aortic aneurysm is a life-threatening disease with limited interventions that is closely related
to vascular smooth muscle cell (VSMC) phenotypic switching. SLC44A2, a member of the …

Venous disease is a term that broadly covers both venous thromboembolic disease and
chronic venous disease. The basic pathophysiology of venous thromboembolism and …

Platelet-neutrophil interactions significantly contribute to the pathophysiology of ischemic
stroke brain injury. Better understanding the mechanisms behind their formation and the …

Venous thromboembolism (VTE) is the third leading cardiovascular cause of death and is
conventionally treated with anticoagulants that directly antagonize coagulation. However …

Platelets are well characterized for their indispensable role in primary hemostasis to control
hemorrhage. Research over the past years has provided a substantial body of evidence …

Earth-abundant metal-based theranostics, agents that integrate diagnostic and therapeutic
functions within the same molecule, may hold the key to the development of low-cost …

Platelets are essential for the formation of a haemostatic plug to prevent bleeding, while
neutrophils are the guardians of our immune defences against invading pathogens. The …