Cuproptosis: p53-regulated metabolic cell death?

C Xiong, H Ling, Q Hao, X Zhou - Cell Death & Differentiation, 2023 - nature.com
Cuproptosis is a novel type of copper-induced cell death that primarily occurs in cells that
utilize oxidative phosphorylation as the main metabolic pathway to produce energy. Copper …

Copper and carcinogenesis

T Theophanides, J Anastassopoulou - Critical reviews in oncology …, 2002 - Elsevier
Metal ions play an important role in biological systems, and without their catalytic presence
in trace or ultratrace amounts many essential co-factors for many biochemical reactions …

Influence of quercetin and rutin on growth and antioxidant defense system of a human hepatoma cell line (HepG2)

M Alía, R Mateos, S Ramos, E Lecumberri… - European journal of …, 2006 - Springer
Background Dietary polyphenols like quercetin and rutin are considered beneficial because
of their potential protective role in the pathogenesis of multiple diseases associated to …

Response of the antioxidant defense system to tert‐butyl hydroperoxide and hydrogen peroxide in a human hepatoma cell line (HepG2)

M Alía, S Ramos, R Mateos, L Bravo… - Journal of biochemical …, 2005 - Wiley Online Library
The aim of this work was to investigate the response of the antioxidant defense system to
two oxidative stressors, hydrogen peroxide and tert‐butyl hydroperoxide, in HepG2 cells in …

Antioxidant activity of protein hydrolysates derived from threadfin bream surimi byproducts

C Wiriyaphan, B Chitsomboon, J Yongsawadigul - Food Chemistry, 2012 - Elsevier
Antioxidant activities of protein hydrolysates from threadfin bream surimi wastes, including
frame, bone and skin (FBS) and refiner discharge (RD), were investigated. FBS and RD …

The human tri-peptide GHK and tissue remodeling

L Pickart - Journal of Biomaterials Science, Polymer Edition, 2008 - Taylor & Francis
Tissue remodeling follows the initial phase of wound healing and stops inflammatory and
scar-forming processes, then restores the normal tissue morphology. The human peptide …

X-ray fluorescence microscopy reveals large-scale relocalization and extracellular translocation of cellular copper during angiogenesis

L Finney, S Mandava, L Ursos… - Proceedings of the …, 2007 - National Acad Sciences
Although copper has been reported to influence numerous proteins known to be important
for angiogenesis, the enhanced sensitivity of this developmental process to copper …

Mechanisms of copper incorporation into human ceruloplasmin

NE Hellman, S Kono, GM Mancini… - Journal of Biological …, 2002 - ASBMB
Ceruloplasmin is a multicopper oxidase essential for normal iron homeostasis. To elucidate
the mechanisms of copper incorporation into this protein, holoceruloplasmin biosynthesis …

Zinc deficiency impairs neuronal precursor cell proliferation and induces apoptosis via p53-mediated mechanisms

RS Corniola, NM Tassabehji, J Hare, G Sharma… - Brain research, 2008 - Elsevier
The potential importance of stem cells in the adult central nervous system (CNS) that cannot
only divide, but also participate in neurogenesis, is now widely appreciated. While we know …

Copper induced upregulation of apoptosis related genes in zebrafish (Danio rerio) gill

A Luzio, SM Monteiro, AA Fontaínhas-Fernandes… - Aquatic toxicology, 2013 - Elsevier
Copper (Cu) is an essential micronutrient that, when present in high concentrations,
becomes toxic to aquatic organisms. It is known that Cu toxicity may induce apoptotic cell …