Signaling pathways involved in colorectal cancer: pathogenesis and targeted therapy

Q Li, S Geng, H Luo, W Wang, YQ Mo, Q Luo… - … and Targeted Therapy, 2024 - nature.com
Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality
worldwide. Its complexity is influenced by various signal transduction networks that govern …

Short-chain fatty acid concentrations in the incidence and risk-stratification of colorectal cancer: a systematic review and meta-analysis

E Alvandi, WKM Wong, MV Joglekar, KJ Spring… - BMC medicine, 2022 - Springer
Background The beneficial role of gut microbiota and bacterial metabolites, including short-
chain fatty acids (SCFAs), is well recognized, although the available literature around their …

Current status and emerging trends in colorectal cancer screening and diagnostics

SS Beniwal, P Lamo, A Kaushik, DL Lorenzo-Villegas… - Biosensors, 2023 - mdpi.com
Colorectal cancer (CRC) is a prevalent and potentially fatal disease categorized based on
its high incidences and mortality rates, which raised the need for effective diagnostic …

State-of-the-art review on immersive virtual reality interventions for colonoscopy-induced anxiety and pain

MA Găină, AS Szalontay, G Ștefănescu… - Journal of clinical …, 2022 - mdpi.com
Background: Colonoscopy related fear impairs the current gold standard screening of
colorectal cancer. Compared to other minimally invasive procedures for cancer screening …

A multi-omics overview of colorectal cancer to address mechanisms of disease, metastasis, patient disparities and outcomes

G Yang, X Yu, DJ Weisenberger, T Lu, G Liang - Cancers, 2023 - mdpi.com
Simple Summary Human colorectal cancer (CRC) is a global health burden, most notably for
minority populations. While screening tools have helped improve disease detection and …

Pioneering biosensor approaches for oral squamous cell carcinoma diagnosis: A comprehensive review

JY Teow, Q Zhang, SAZ Abidin, CC Tan… - Process …, 2024 - Elsevier
Oral squamous cell carcinoma (OSCC) remains a significant global challenge in the medical
field, accounting for approximately 300,000 incidences and 145,000 mortalities annually …

Epigenetics in the diagnosis and prognosis of head and neck cancer: A systematic review

I Lim, J Tan, A Alam, M Idrees… - Journal of Oral …, 2024 - Wiley Online Library
Background Aberrant epigenetic modifications significantly develop and progress human
malignancies including head and neck squamous cell carcinoma (HNSCC). Taking into …

Advances in blood DNA methylation-based assay for colorectal cancer early detection: a systematic updated review

M Khabbazpour, M Tat, A Karbasi… - … from Bed to Bench, 2024 - pmc.ncbi.nlm.nih.gov
Aim: A systematic review was conducted to summarize the methylated circulating tumor DNA
(ctDNA) markers reported over the last decade for early detection of colorectal cancer (CRC) …

Single-cell RNA-Seq and bulk RNA-Seq reveal reliable diagnostic and prognostic biomarkers for CRC

X Zhang, L Yang, Y Deng, Z Huang, H Huang… - Journal of Cancer …, 2023 - Springer
Purpose The potential role of epithelium-specific genes through the adenoma-carcinoma
sequence in the development of colorectal cancer (CRC) remains unknown. Therefore, we …

Association between colorectal cancer and expression levels of miR-21, miR-17-5P, miR-155 genes and the presence of Fusobacterium nucleatum in biopsy …

N Bostanshirin, B Hajikhani, AA Vaezi… - Infectious Agents and …, 2023 - Springer
Background Colorectal cancer (CRC) is considered the second-deadliest and third-most
common malignancy worldwide. Studying the carcinogenic mechanism of bacteria or their …