The Fasciclin 1 (FAS1) domain is an ancient structural motif in extracellular proteins present
in all kingdoms of life and particularly abundant in plants. The FAS1 domain accommodates …

Transforming growth factor-β-induced protein (TGFBIp), an extracellular matrix protein, is the
second most abundant protein in the corneal stroma. In this review, we summarize the …

Human periostin is a 78–91 kDa matricellular protein implicated in extracellular matrix
remodeling, tumor development, metastasis, and inflammatory diseases like atopic …

Matricellular proteins (MCPs) are defined as extracellular matrix (ECM) associated proteins
that are important regulators and integrators of microenvironmental signals, contributing to …

Approaches for studying the evolution of globular proteins are now well established yet are
unsuitable for disordered sequences. Our understanding of the evolution of proteins …

TGFBI p is a constituent of the extracellular matrix in many human tissues including the
cornea, where it is one of the most abundant proteins expressed. TGFBI p interacts with …

Fasciclins (FAS1) are ancient adhesion protein domains with no common small ligand
binding reported. A unique microalgal FAS1-containing astaxanthin (AXT)-binding protein …

Human periostin plays a multifaceted role in remodeling the extracellular matrix milieu by
interacting with other proteins and itself in both a heterophilic and homophilic manner …

Purpose: The study aims to identify genetic variants in five Chinese families with
Keratoconus (KC) and describe the characteristics of parental corneal topography. Methods …

The protein periostin is a matricellular protein that is expressed in connective tissue. It is
composed of five globular domains arranged in an elongated structure with an extensive …