Hydrogels, as interconnected networks (polymer mesh; physically, chemically, or dynamic
crosslinked networks) incorporating a high amount of water, present structural …

Biological materials such as extracellular matrix scaffolds, cancer cells, and tissues are often
assumed to respond elastically for simplicity; the viscoelastic response is quite commonly …

In mammals, mechanics at multiple stages—nucleus to cell to ECM—underlie multiple
physiological and pathological functions from its development to reproduction to death …

Controlling rheological properties offers the opportunity to gain insight into the physical
characteristics, structure, stability and drug release rate of formulations. To better understand …

The mechanical behavior of soft tissue extracellular matrix is time dependent. Moreover, it
evolves over time due to physiological processes as well as aging and disease. Measuring …

The development of commercial collagen inks for extrusion-based bioprinting has increased
the amount of research on pure collagen bioprinting, ie, collagen inks not mixed with gelatin …

Collagen has grown increasingly present in bioprinting, however collagen bioprinting has
mostly been limited to the extrusion printing of collagen type I to form weak collagen …

Neural stem cells-based therapies have shown great potential for central nervous system
regeneration, with three-dimensional (3D) culture systems representing a key technique for …

Biomaterials science is a multidisciplinary field based on the reciprocal interaction between
different disciplines such as materials science, biology, and biomechanics. This chapter …

Directed cell migration plays a crucial role in physiological and pathological conditions. One
important mechanical cue, known to influence cell migration, is the gradient of substrate …