Targeted delivery combined with controlled drug release has a pivotal role in the future of
personalized medicine. This review covers the principles, advantages, and drawbacks of …

Nanoparticles (NPs) have emerged as an effective modality for the treatment of various
diseases including cancer, cardiovascular and inflammatory diseases. Various forms of NPs …

Polymers have played an integral role in the advancement of drug delivery technology by
providing controlled release of therapeutic agents in constant doses over long periods …

The term “polymer therapeutics” was coined to describe polymeric drugs, polymer
conjugates of proteins, drugs and aptamers, together with those block copolymer micelles …

The discovery of new molecular targets and the subsequent development of novel
anticancer agents are opening new possibilities for drug combination therapy as anticancer …

Cell penetrating peptides hold considerable potential for academic and pharmaceutical
remits with an interest in delivering macromolecules to the insides of cells. Hundreds of …

Partly PEGylated polyamidoamine (PAMAM) dendrimers were used as the carrier for tumor-
selective targeting of the anticancer drug doxorubicin (DOX). Acid-sensitive cis-aconityl …

Disseminated metastatic breast cancer needs aggressive treatment due to its reduced
response to anticancer treatment and hence low survival and quality of life. Although in …

The concept of polymer–drug conjugates was proposed more than 30 years ago, and an N-
(2-hydroxypropyl) methacrylamide (HPMA) copolymer conjugate of doxorubicin covalently …

Copolymers of N-(2-hydroxypropyl) methacrylamide (HPMA) are prototypic and well-
characterized polymeric drug carriers that have been broadly implemented in the delivery of …