Therapeutic potential of bacteriophage endolysins for infections caused by Gram-positive bacteria

H Liu, Z Hu, M Li, Y Yang, S Lu, X Rao - Journal of biomedical science, 2023 - Springer
Abstract Gram-positive (G+) bacterial infection is a great burden to both healthcare and
community medical resources. As a result of the increasing prevalence of multidrug-resistant …

Nanotechnology based approaches in phage therapy: overcoming the pharmacological barriers

S Kaur, A Kumari, A Kumari Negi, V Galav… - Frontiers in …, 2021 - frontiersin.org
With the emergence and spread of global antibiotic resistance and the need for searching
safer alternatives, there has been resurgence in exploring the use of bacteriophages in the …

[HTML][HTML] Enhancing the stability and bio-accessibility of carotenoids extracted from canistel (Lucuma nervosa) via liposomes encapsulation

X Liu, X Lin, Y Wei, T Fei, X Hu, L Wang - LWT, 2024 - Elsevier
Canistel (Lucuma nervosa) is a valuable natural source of carotenoids, but their use in the
food industry is hampered by low extraction efficiency, poor stability, and limited bio …

Liposomes-based drug delivery systems of anti-biofilm agents to combat bacterial biofilm formation

Z Makhlouf, AA Ali, MH Al-Sayah - Antibiotics, 2023 - mdpi.com
All currently approved antibiotics are being met by some degree of resistance by the
bacteria they target. Biofilm formation is one of the crucial enablers of bacterial resistance …

Characterization of a Peptidoglycan-Degrading Protein: Biochemical and Antimicrobial Characteristics, Antibiotic Synergism, and Delivery System Innovation

VC Oliveira, NG Rosa-Garzon, ACSD Rocha… - Probiotics and …, 2024 - Springer
The global health threat posed by antibiotic resistance has led to new research involving
bacteriophage-encoded enzymes. This study characterized a new peptidoglycan-degrading …

Localized drug delivery to the middle ear: Recent advances and perspectives for the treatment of middle and inner ear diseases

M Magdy, E Elmowafy, M Elassal, RAH Ishak - Journal of Drug Delivery …, 2022 - Elsevier
Traditionally, the majority of ototopical delivery systems are conventional medicated ear
drops. However, their endurance and wide utility is jeopardized due to the presence of an …

Novel antimicrobial treatment strategy based on drug delivery systems for acute otitis media

M Kono, NK Umar, S Takeda, M Ohtani… - Frontiers in …, 2021 - frontiersin.org
Despite tremendous success of pneumococcal conjugated vaccine and antimicrobial
treatment by amoxicillin, acute otitis media (AOM) still remains as a great medical concern …

Liposomal Delivery of Newly Identified Prophage Lysins in a Pseudomonas aeruginosa Model

D Morais, L Tanoeiro, AT Marques… - International Journal of …, 2022 - mdpi.com
Pseudomonas aeruginosa is a Gram-negative opportunistic bacterium that presents
resistance to several antibiotics, thus, representing a major threat to human and animal …

Biomaterials for non-invasive trans-tympanic drug delivery: requirements, recent advances and perspectives

Y Xu, Z Bei, M Li, K Qiu, J Ren, B Chu… - Journal of Materials …, 2024 - pubs.rsc.org
Various non-invasive delivery systems have recently been developed as an alternative to
conventional injections. Local transdermal administration represents the most attractive …

Janus mesoporous organosilica/platinum nanomotors for active treatment of suppurative otitis media

Z Luo, R Wang, X Deng, T Chen, X Ma, Y Zhang… - Nanoscale, 2024 - pubs.rsc.org
We report a Janus mesoporous organosilica/platinum (MOS/Pt) nanomotor for active
targeted treatment of suppurative otitis media, as a new type of multi-functional ear drop. The …