The enzymatic breakdown of carbohydrates plays a critical role in several biological events
and enables the development of sustainable processes to obtain bioproducts and biofuels …

Abstract Dendrobium officinale (Tie-Pi-Shi-Hu) is a precious traditional Chinese medicine
(TCM). The principal active components are polysaccharides (DOP), which have a high …

Akkermansia muciniphila is a mucin-degrading bacterium commonly found in the human gut
that promotes a beneficial effect on health, likely based on the regulation of mucus thickness …

Xylanolytic enzymes from glycoside hydrolase family 43 (GH43) are involved in the
breakdown of hemicellulose, the second most abundant carbohydrate in plants. Here, we …

Background Secondary metabolites as natural products from endophytic fungi are important
sources of pharmaceuticals. However, there is currently little understanding of endophytic …

Xanthomonas plant pathogens can infect hundreds of agricultural plants. These bacteria
exploit sophisticated molecular strategies based on multiple secretion systems and their …

Bifidobacteria represent one of the first colonizers of human gut microbiota, providing to this
ecosystem better health and nutrition. To maintain a mutualistic relationship, they have …

Rational design is an important tool for sculpting functional and stability properties of
proteins and its potential can be much magnified when combined with in vitro and natural …

The glycoside hydrolase family 39 (GH39) is a functionally expanding family with limited
understanding about the molecular basis for substrate specificity and extremophilicity. In this …

Abstract Cold-adapted endo-β-1, 4-glucanases hold great potential for industrial processes
requiring high activity at mild temperatures such as in food processing and extraction of …