Photo‐and Redox‐Regulated Transmembrane Ion Transporters

M Ahmad, SA Gartland… - Angewandte Chemie …, 2023 - Wiley Online Library
Synthetic supramolecular ion transporters find applications as potential therapeutics and as
tools for engineering functional membranes. Stimuli‐responsive systems enable external …

Anion transporters based on halogen, chalcogen, and pnictogen bonds: towards biological applications

A Singh, A Torres-Huerta, F Meyer, H Valkenier - Chemical science, 2024 - pubs.rsc.org
Motivated by their potential biological applications, anion receptors are increasingly
explored as transmembrane transporters for anions. The vast majority of the reported anion …

Exploiting the Catenane Mechanical Bond Effect for Selective Halide Anion Transmembrane Transport

H Min Tay, TG Johnson, A Docker… - Angewandte Chemie …, 2023 - Wiley Online Library
The first examples of [2] catenanes capable of selective anion transport across a lipid bilayer
are reported. The neutral halogen bonding (XB)[2] catenanes were prepared via a chloride …

Inter‐Vesicle Signal Transduction Using a Photo‐Responsive Zinc Ionophore

SA Gartland, TG Johnson, E Walkley… - Angewandte Chemie …, 2023 - Wiley Online Library
Transmission of chemical information between cells and across lipid bilayer membranes is
of profound significance in many biological processes. The design of synthetic signalling …

Photocontrolled activation of doubly o-nitrobenzyl-protected small molecule benzimidazoles leads to cancer cell death

M Ahmad, NJ Roy, A Singh, D Mondal, A Mondal… - Chemical …, 2023 - pubs.rsc.org
Artificial biomimetic chloride anionophores have shown promising applications as
anticancer scaffolds. Importantly, stimuli-responsive chloride transporters that can be …

Solution Studies of a Water-Stable, Trivalent Antimony Pnictogen Bonding Anion Receptor with High Binding Affinities for CN, OCN, and OAc

J Qiu, CN Bateman, S Lu, GC George III, X Li… - Inorganic …, 2023 - ACS Publications
The solution phase anion binding behavior of a water-stable bidentate pnictogen bond
donor was studied. A modest change in the visible absorption spectrum allowed for the …

The Missing Chalcogen Bonding Donor: Strongly Polarized Oxygen of Water

Q Zhang, K Luo, W Zhou, A Li, Q He - Journal of the American …, 2024 - ACS Publications
A biscyclen molecular cabin, synthesized by connecting two cyclen macrocycles with four
linkages, entraps a Li+··· H2O··· Li+ trimer with a water molecule clamped by two Li+ ions …

Responsive Anionophores with AND Logic Multi‐Stimuli Activation

M Ahmad, TG Johnson, M Flerin, F Duarte… - Angewandte …, 2024 - Wiley Online Library
Artificial ion transport systems have emerged as an important class of compounds that
promise applications in chemotherapeutics as anticancer agents or to treat channelopathies …

Transmembrane anion transport mediated by sigma-hole interactions

A Docker, MJ Langton - Trends in Chemistry, 2023 - cell.com
Supramolecular transmembrane anion transporters are promising therapeutics for
channelopathies and typically operate via hydrogen bonding. Sigma-hole interactions …

Transmembrane Delivery of an Aryl Azopyrazole Photo‐switchable Ion Transporter Relay

E Grählert, MJ Langton - Angewandte Chemie International …, 2024 - Wiley Online Library
Stimuli‐responsive synthetic ionophores allow for spatial and temporal control over ion
transport, with promise for applications in targeted therapy. Relay transporters have …