The protein kinase, GSK-3, participates in diverse biological processes and is now
recognized a promising drug discovery target in treating multiple pathological conditions …

Over a decade of schizophrenia research using human induced pluripotent stem cell (iPSC)-
derived neural models has provided substantial data describing neurobiological …

Neurons derived from human induced pluripotent stem cells (hiPSCs) have been used to
model basic cellular aspects of neuropsychiatric disorders, but the relationship between the …

Neuropsychiatric disorders affect a large proportion of the global population and there is an
urgent need to understand the pathogenesis and to develop novel and improved treatments …

Coronavirus disease 2019 (COVID-19) pandemic is caused by the novel coronavirus that
has spread rapidly around the world, leading to high mortality because of multiple organ …

Glycogen synthase kinase 3β (GSK3) is a multifaceted serine/threonine (S/T) kinase
expressed in all eukaryotic cells. GSK3β is highly enriched in neurons in the central nervous …

Background The pathogenesis of schizophrenia is still unknown. Nearly a half of
schizophrenic patients have depressive symptoms and even some impulsive behaviors. The …

The cellular pathology of schizophrenia and the potential of antipsychotics to target
underlying neuronal dysfunctions are still largely unknown. We employed glutamatergic …

Aims Epidemiological studies demonstrate an association between classes of obesity and
psychiatric disorders, although little is known about shared genetics and causality of …

Introduction Human-derived induced pluripotent stem cell (iPSC) models of brain promise to
advance our understanding of neurotoxic consequences of drug use. However, how well …