Growth and division of the peptidoglycan matrix

PDA Rohs, TG Bernhardt - Annual review of microbiology, 2021 - annualreviews.org
Most bacteria are surrounded by a peptidoglycan cell wall that defines their shape and
protects them from osmotic lysis. The expansion and division of this structure therefore plays …

Cell wall peptidoglycan in Mycobacterium tuberculosis: An Achilles' heel for the TB-causing pathogen

A Maitra, T Munshi, J Healy, LT Martin… - FEMS microbiology …, 2019 - academic.oup.com
Tuberculosis (TB), caused by the intracellular pathogen Mycobacterium tuberculosis,
remains one of the leading causes of mortality across the world. There is an urgent …

The architecture of the Gram-positive bacterial cell wall

L Pasquina-Lemonche, J Burns, RD Turner, S Kumar… - Nature, 2020 - nature.com
The primary structural component of the bacterial cell wall is peptidoglycan, which is
essential for viability and the synthesis of which is the target for crucial antibiotics …

Peptidoglycan: structure, synthesis, and regulation

S Garde, PK Chodisetti, M Reddy - EcoSal Plus, 2021 - Am Soc Microbiol
Peptidoglycan is a defining feature of the bacterial cell wall. Initially identified as a target of
the revolutionary beta-lactam antibiotics, peptidoglycan has become a subject of much …

Cytoplasmic condensation induced by membrane damage is associated with antibiotic lethality

F Wong, JM Stokes, B Cervantes, S Penkov… - Nature …, 2021 - nature.com
Bactericidal antibiotics kill bacteria by perturbing various cellular targets and processes.
Disruption of the primary antibiotic-binding partner induces a cascade of molecular events …

Bacillus subtilis cell diameter is determined by the opposing actions of two distinct cell wall synthetic systems

MF Dion, M Kapoor, Y Sun, S Wilson, J Ryan… - Nature …, 2019 - nature.com
Rod-shaped bacteria grow by adding material into their cell wall via the action of two
spatially distinct enzymatic systems: the Rod complex moves around the cell circumference …

Bacterial cell wall quality control during environmental stress

EA Mueller, PA Levin - MBio, 2020 - Am Soc Microbiol
Single-celled organisms must adapt their physiology to persist and propagate across a wide
range of environmental conditions. The growth and division of bacterial cells depend on …

Structure and function of the Arctic and Antarctic marine microbiota as revealed by metagenomics

S Cao, W Zhang, W Ding, M Wang, S Fan, B Yang… - Microbiome, 2020 - Springer
Abstract Background The Arctic and Antarctic are the two most geographically distant
bioregions on earth. Recent sampling efforts and following metagenomics have shed light …

AFM in cellular and molecular microbiology

YF Dufrêne, A Viljoen, J Mignolet… - Cellular …, 2021 - Wiley Online Library
The unique capabilities of the atomic force microscope (AFM), including super‐resolution
imaging, piconewton force‐sensitivity, nanomanipulation and ability to work under …

Structure and mechanism of the proton-driven motor that powers type 9 secretion and gliding motility

R Hennell James, JC Deme, A Kjӕr, F Alcock… - Nature …, 2021 - nature.com
Three classes of ion-driven protein motors have been identified to date: ATP synthase, the
bacterial flagellar motor and a proton-driven motor that powers gliding motility and the type 9 …