Pericytes are a type of mural cell located between the endothelial cells of capillaries and the
basement membrane, which function to regulate the capillary vasomotor and maintain …

Cost-efficacy of currently applied treatments is an issue in overall cancer management
challenging healthcare and causing tremendous economic burden to societies around the …

Cancer immunotherapy has proven remarkably successful through instigation of systemic
antitumor T cell responses. Despite this achievement, further advancements are needed to …

Simple Summary Cancer is a global health problem with severe consequences. Certain
genes, known as transcription factors (TFs), are overactive in many tumors. Targeting these …

Recent advances in the treatment of various cancers have resulted in the adaptation of
several novel immunotherapeutic strategies. Notably, the recent intervention through …

Background Immunotherapy has been shown to be effective as a first-line treatment option
for non-small cell lung cancer (NSCLC) patients. Unfortunately, it has failed to acquire an …

Background Lipid metabolic reprogramming in colon cancer shows a potential impact on
tumor immune microenvironment and is associated with response to immunotherapy …

Nanomedicines for antitumour therapy have been widely studied in recent decades, but only
a few have been used in clinical applications. One of the most important reasons is the poor …

Lung cancer remains one of the major causes of cancer-related death globally. Recent
studies have shown that aberrant m6A levels caused by METTL3 are involved in the …

PD-1 pathway blockade has been shown to promote proatherogenic T-cell responses and
destabilization of atherosclerotic plaques. Moreover, preclinical evidence suggests a …