Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) is one of the
most widely used techniques in proteomics to achieve structural identification and …

Since calcium and phosphorus play vital roles in a multitude of physiologic systems,
disorders of calcium and phosphorus metabolism always lead to severe consequences such …

Small cell lung carcinoma (SCLC) is a highly aggressive cancer with low survival rate.
Although initial response to chemotherapy in SCLC patients is well‐rated, the treatments …

Background Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related
deaths worldwide. Complete epithelial to mesenchymal transition (EMT) has long been …

Mass spectrometry (MS) is an essential analytical technology on which the emerging omics
domains; such as genomics; transcriptomics; proteomics and metabolomics; are based. This …

Parathyroid carcinoma (PCa) is a rare endocrine neoplasia that typically has unfavourable
outcomes. The contribution of long non-coding RNAs (lncRNAs) to the development of …

Introduction Primary HPT (PHPT) is a common disorder, affecting approximately 1% of the
general population. Parathyroid adenomas emerge as non-familial sporadic in 90% of …

Background/Aim: The lack of specific parathyroid carcinoma (PC) biomarkers in clinical
practice points out the importance of analyzing the proteomic signature of this cancer. We …

Rationale Explorative statistical analysis of mass spectrometry data is still a time‐consuming
step. We analyzed critical factors for application of principal component analysis (PCA) in …

Background/Aim: Breast cancer (BC) incidence and mortality rates have been increasing
due to the lack of appropriate diagnostic tools for early detection. Proteomics-based studies …