Permanent fibrosis and chronic deterioration of heart function in patients after myocardial
infarction present a major health-care burden worldwide. In contrast to the restricted …

Understanding the cellular and molecular determinants of mammalian tissue regeneration
and repair is crucial for developing effective therapies that restore tissue architecture and …

Ischemic heart disease and by extension myocardial infarction is the primary cause of death
worldwide, warranting regenerative therapies to restore heart function. Current models of …

The epicardium, previously viewed as a passive outer layer around the heart, is now
recognized as an essential component in development, regeneration, and repair. In this …

In contrast to other mammals, the spiny mouse (Acomys) regenerates skin and ear tissue,
which includes hair follicles, glands, and cartilage, in a scar-free manner. Ear punch …

Although most mammals heal injured tissues and organs with scarring, spiny mice (Acomys)
naturally regenerate skin and complex musculoskeletal tissues. Now, the core signaling …

Background In recent years, the African spiny mouse Acomys cahirinus has been shown to
regenerate a remarkable array of severe internal and external injuries in the absence of a …

Interest in vertebrate cardiac regeneration has exploded over the past two decades since
the discovery that adult zebrafish are capable of complete heart regeneration, contrasting …

The nonapeptide system modulates numerous social behaviors through oxytocin and
vasopressin activation of the oxytocin receptor (OXTR) and vasopressin receptor (AVPR1A) …

ABSTRACT The African spiny mouse (Acomys cahirinus) is a unique mammalian model of
tissue regeneration, regenerating 4 mm ear-hole punches with cartilage, adipocytes, hair …