Due to increasingly limited water resources, diminishing farmland acreage, and potentially
negative effects of climate change, an urgent need exists to improve agricultural productivity …

The flavonoid pathway is one of the best characterized specialized metabolite pathways of
plants. In angiosperms, the flavonoids have varied roles in assisting with tolerance to abiotic …

Esophageal cancer is a unique and complex heterogeneous malignancy, with substantial
tumor heterogeneity: at the cellular levels, tumors are composed of tumor and stromal …

Resveratrol (3, 4, 5-trihydroxystilbene) is a naturally occurring polyphenolic stilbene
compound produced by certain plant species in response to biotic and abiotic factors …

Adaptive laboratory evolution (ALE) is an evolutionary engineering approach in artificial
conditions that improves organisms through the imitation of natural evolution. Due to the …

Highlights•Genome-scale models are available for many industrially important
fungi.•Enzyme-constrained genome-scale models improve simulation …

Medicinal and aromatic plants possess pharmacological properties (antidiabetes,
anticancer, antihypertension, anticardiovascular, antileprosy, etc.) because of their potential …

Although heeding and leading in the application perspective, we are lagging to address the
variegated cross-talks involved in plant-endophyte interactions, the basis for the pertinence …

Recent investigations carried out all over the world have disclosed the capacity of a
multitude of endophytic fungal species/strains to produce bioactive compounds which are …

Abstract “In silico organisms” are computational genome-scale metabolic models used in
systems and synthetic biology developed by constraint-based metabolic simulations using …