Pediatric central nervous system (CNS) tumors are the second most common childhood
malignancy and the most common solid tumor in children. The incidence rate of childhood …

Atypical teratoid/rhabdoid tumors (ATRTs) typically arise in the central nervous system
(CNS) of children under 3 years of age. Despite intensive multimodal therapy (surgery …

Rhabdoid tumor predisposition syndrome (RTPS) is characterized by a markedly increased
risk for the development of rhabdoid tumors–rare and highly aggressive malignant tumors …

Background Controversy exists as to what may be defined as standard of care (including
markers for stratification) for patients with atypical teratoid/rhabdoid tumors (ATRTs). The …

Purpose: Report relevance of molecular groups to clinicopathologic features, germline
SMARCB1/SMARCA4 alterations (GLA), and survival of children with atypical teratoid …

Malignant rhabdoid tumors (MRT) are highly aggressive pediatric cancers that respond
poorly to current therapies. In this study, we screened several MRT cell lines with large-scale …

Purpose Proton radiation therapy is commonly used in young children with brain tumors for
its potential to reduce late effects. However, some proton series report higher rates of …

ABSTRACT Introduction: Malignant Rhabdoid Tumor (MRT) is a rare and highly aggressive
malignancy primarily affecting infants and young children. The most common anatomic …

Abstract Purpose of Review: This article describes the most common pediatric brain tumors
and highlights recent developments in their diagnosis and treatment strategies. Recent …

Atypical teratoid/rhabdoid tumor (AT/RT) is a rare CNS cancer that typically occurs in
children younger than 3 years of age. Histologically, AT/RTs are embryonal tumors that …