Caenorhabditis elegans has become a powerful experimental organism with which to study
meiotic processes that promote the accurate segregation of chromosomes during the …

The origin of the p53 superfamily predates animal evolution and first appears in unicellular
Flagellates. Invertebrate p53 superfamily members appear to have a p63-like domain …

Repair of the programmed meiotic double-strand breaks (DSBs) that initiate recombination
must be coordinated with homolog pairing to generate crossovers capable of directing …

Meiotic crossovers (COs) are tightly regulated to ensure that COs on the same chromosome
are distributed far apart (crossover interference, COI) and that at least one CO is formed per …

Concerns about the safety of Bisphenol A, a chemical found in plastics, receipts, food
packaging and more, have led to its replacement with substitutes now found in a multitude of …

Recombination between homologous chromosomes of different parental origin (homologs)
is necessary for their accurate segregation during meiosis. It has been suggested that …

Homologous recombination (HR) is essential for repair of meiotic DNA double-strand breaks
(DSBs). Although the mechanisms of RAD-51-DNA filament assembly and strand exchange …

The breast and ovarian cancer susceptibility protein BRCA1 is evolutionarily conserved and
functions in DNA double‐strand break (DSB) repair through homologous recombination, but …

Mutations that enhance the response to double-stranded RNA (dsRNA) have revealed
components of the RNA interference (RNAi) pathway or related small RNA pathways. To …

R‐loops are harmful structures with a negative impact on transcription and recombination
during mitosis, but no information exists for meiosis. We used Saccharomyces cerevisiae …