Origins of human disease: the chrono-epigenetic perspective

ES Oh, A Petronis - Nature Reviews Genetics, 2021 - nature.com
Epigenetics has enriched human disease studies by adding new interpretations to disease
features that cannot be explained by genetic and environmental factors. However …

[HTML][HTML] Can melatonin reduce the severity of post-COVID-19 syndrome?

A Souissi, I Dergaa, M Romdhani, A Ghram… - EXCLI …, 2023 - ncbi.nlm.nih.gov
This short review aimed at (i) providing an update on the health benefits associated with
melatonin supplementation, while (ii) considering future potential research directions …

Effects of melatonin on protecting against lung injury

W Wang, J Gao - Experimental and Therapeutic …, 2021 - spandidos-publications.com
Abstract Melatonin (MT; N‑acetyl‑5‑methoxy‑tryptamine), which has multiple effects and
roles, is secreted from the pineal gland at night according to the daily rhythm. In addition to …

Melatonin Prevents Alcohol-and Metabolic Dysfunction-Associated Steatotic Liver Disease by Mitigating Gut Dysbiosis, Intestinal Barrier Dysfunction, and …

KR LeFort, W Rungratanawanich, BJ Song - Antioxidants, 2023 - mdpi.com
Melatonin (MT) has often been used to support good sleep quality, especially during the
COVID-19 pandemic, as many have suffered from stress-related disrupted sleep patterns. It …

Protective Effects of Melatonin on Saccharomyces cerevisiae under Ethanol Stress

M Sunyer-Figueres, A Mas, G Beltran, MJ Torija - Antioxidants, 2021 - mdpi.com
During alcoholic fermentation, Saccharomyces cerevisiae is subjected to several stresses,
among which ethanol is of capital importance. Melatonin, a bioactive molecule synthesized …

Alcohol and melatonin

N Kurhaluk - Chronobiology international, 2021 - Taylor & Francis
Investigation of the pathogenesis of alcoholism in humans using different methodological
approaches has facilitated detection of important biological factors of consequent metabolic …

Effects of melatonin and metformin in preventing lysosome-induced autophagy and oxidative stress in rat models of carcinogenesis and the impact of high-fat diet

N Kurhaluk, H Tkachenko - Scientific reports, 2022 - nature.com
Imbalanced glucose tolerance and insulin resistance remain important as high cancer risk
factors. Metformin administration to diabetic patients may be associated with a reduced risk …

Sudden infant death syndrome: Melatonin, serotonin, and CD34 factor as possible diagnostic markers and prophylactic targets

D Ivanov, E Mironova, V Polyakova, I Evsyukova… - PLoS …, 2021 - journals.plos.org
Sudden infant death syndrome (SIDS) is one of the primary causes of death of infants in the
first year of life. According to the WHO's data, the global infant mortality rate is 0.64–2 per …

Effect of night-shift work on cortisol circadian rhythm and melatonin levels

MCB Brum, MB Senger, CC Schnorr, LR Ehlert… - Sleep …, 2022 - thieme-connect.com
Objectives Night-shift work has been associated with several negative effects on worker's
health, possibly due to circadian desynchronization, sleep deprivation and suppression of …

Disrupted diurnal oscillations of the gut microbiota in patients with alcohol dependence

K Zhao, Z Ni, Y Qin, R Zhu, Z Yu, Y Ma… - Frontiers in Cellular …, 2023 - frontiersin.org
Background Patients with alcohol dependence (AD) can exhibit gut dysbacteria. Dysbacteria
may co-occur with disruptions of circadian rhythmicity of the gut flora, which can aggravate …