mTOR: Its Critical Role in Metabolic Diseases, Cancer, and the Aging Process

SK Marafie, F Al-Mulla, J Abubaker - International Journal of Molecular …, 2024 - mdpi.com
The mammalian target of rapamycin (mTOR) is a pivotal regulator, integrating diverse
environmental signals to control fundamental cellular functions, such as protein synthesis …

[HTML][HTML] In Vitro Evaluation of Antipseudomonal Activity and Safety Profile of Peptidomimetic Furin Inhibitors

S Maluck, R Bobrovsky, M Poór, RW Lange… - Biomedicines, 2024 - mdpi.com
Inhibitors of the serine protease furin have been widely studied as antimicrobial agents due
to their ability to block the cleavage and activation of certain viral surface proteins and …

Is diabetes a real susceptibility for SARS-CoV-2 oral manifestation?

T Smitha, A Thomas - Journal of Oral and Maxillofacial Pathology, 2023 - journals.lww.com
Background: Furin, a polybasic cleavage enzyme, is increasingly recognized in the
pathogenesis of metabolic syndromes like diabetes. Its cleavage action is an essential …

Evaluation of serum level of furin enzyme activity, fatty acid binding protein-4 (FABP-4) and insulin resistance in patients with pre-diabetes and newly diagnosed type 2 …

ZS Obaid, EAR Al-Wasiti, FA Deli - Anaesthesia, Pain & …, 2024 - apicareonline.com
Objectives: To study the levels of furin enzyme activity (FEA) and fatty acid binding protein-4
(FABP-4) in the serum as vital indicators in pre-diabetes patients, newly diagnosed type 2 …