Systems biology of personalized nutrition

B van Ommen, T van den Broek, I de Hoogh… - Nutrition …, 2017 - academic.oup.com
Personalized nutrition is fast becoming a reality due to a number of technological, scientific,
and societal developments that complement and extend current public health nutrition …

Modeling-enabled systems nutritional immunology

M Verma, R Hontecillas, V Abedi, A Leber… - Frontiers in …, 2016 - frontiersin.org
This review highlights the fundamental role of nutrition in the maintenance of health, the
immune response, and disease prevention. Emerging global mechanistic insights in the field …

Navigating the disease landscape: knowledge representations for contextualizing molecular signatures

M Saqi, A Lysenko, YK Guo, T Tsunoda… - Briefings in …, 2019 - academic.oup.com
Large amounts of data emerging from experiments in molecular medicine are leading to the
identification of molecular signatures associated with disease subtypes. The …

Systems view of adipogenesis via novel omics-driven and tissue-specific activity scoring of network functional modules

I Nassiri, R Lombardo, M Lauria, MJ Morine… - Scientific reports, 2016 - nature.com
The investigation of the complex processes involved in cellular differentiation must be based
on unbiased, high throughput data processing methods to identify relevant biological …

Human nutrition, environment, and health

J Kaput, M Kussmann, M Radonjic, F Virgili, G Perozzi - Genes & nutrition, 2015 - Springer
Improving health of individuals who consume too many or too few calories or inadequate
levels of micro-and macronutrients remains a major challenge for today's world. Providing …

Propelling the paradigm shift from reductionism to systems nutrition

J Kaput, G Perozzi, M Radonjic, F Virgili - Genes & Nutrition, 2017 - Springer
The complex physiology of living organisms represents a challenge for mechanistic
understanding of the action of dietary bioactives in the human body and of their possible role …

The future of protein biomarker research in type 2 diabetes mellitus

R Tans, L Verschuren, HJCT Wessels… - Expert review of …, 2019 - Taylor & Francis
Introduction: The onset of type 2 diabetes mellitus (T2DM) is strongly associated with obesity
and subsequent perturbations in immuno-metabolic responses. To understand the …

Network-based integration of molecular and physiological data elucidates regulatory mechanisms underlying adaptation to high-fat diet

D Derous, T Kelder, EM van Schothorst, M van Erk… - Genes & Nutrition, 2015 - Springer
Health is influenced by interplay of molecular, physiological and environmental factors. To
effectively maintain health and prevent disease, health-relevant relations need to be …

Nutrigenomics and Transcriptomics for a Personalized Nutrition

N Habib, A Idrissi Azami, K Aberkani, I Motaib… - Nutrition and Human …, 2022 - Springer
The field of nutrigenomics encompasses multiple approaches aimed at understanding the
effects of diet and dietary components on growth, health, and disease development of living …

[PDF][PDF] Differentiation of paired human subcutaneous and visceral adipose tissues by holistic proteome profiling using LC-MS/MS: a pilot study

PMM van Haard, P Herbrink… - International Journal of …, 2016 - researchgate.net
Background: We examined, for the first time proteins expressions and abundancies within
paired human subcutaneous (SAT) and visceral adipose tissues (VAT), using equal …