Cortical synaptic architecture supports flexible sensory computations

B Scholl, D Fitzpatrick - Current opinion in neurobiology, 2020 - Elsevier
Highlights•Functional properties of excitatory inputs onto cortical neurons are more
diverse.•Cortical neurons can receive imbalanced synaptic excitation and inhibition.•Current …

A model for the origin of motion direction selectivity in visual cortex

AW Freeman - Journal of Neuroscience, 2021 - Soc Neuroscience
Motion perception is a vital part of our sensory repertoire in that it contributes to navigation,
awareness of moving objects, and communication. Motion sense in carnivores and primates …

Astrocyte coverage of excitatory synapses correlates to measures of synapse structure and function in ferret primary visual cortex

CI Thomas, MA Ryan, MC McNabb, N Kamasawa… - Glia, 2024 - Wiley Online Library
Most excitatory synapses in the mammalian brain are contacted or ensheathed by astrocyte
processes, forming tripartite synapses. Astrocytes are thought to be critical regulators of the …

Developmental alignment of feedforward inputs and recurrent network activity drives increased response selectivity and reliability in primary visual cortex following the …

AA Lempel, D Fitzpatrick - bioRxiv, 2023 - biorxiv.org
Selective and reliable cortical sensory representations depend on synaptic interactions
between feedforward inputs, conveying information from lower levels of the sensory …

Development of visual response selectivity in cortical GABAergic interneurons

JT Chang, D Fitzpatrick - Nature Communications, 2022 - nature.com
The visual cortex of carnivores and primates displays a high degree of modular network
organization characterized by local clustering and structured long-range correlations of …

Mirrored might: A vision for inhibition

LA Koek, B Scholl - Neuron, 2024 - Elsevier
Mirrored might: A vision for inhibition - ScienceDirect Skip to main contentSkip to article
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Mechanism underpinning the sharpening of orientation and spatial frequency selectivities in the tree shrew (Tupaia belangeri) primary visual cortex

YS Mohan, S Viswanathan, J Jayakumar… - Brain Structure and …, 2022 - Springer
Most neurons in the primary visual cortex (V1) of mammals show sharp orientation selectivity
and band-pass spatial frequency tuning. Here, we examine whether sharpening of the broad …

A model for the development of binocular congruence in primary visual cortex

MA Somaratna, AW Freeman - Scientific Reports, 2022 - nature.com
Neurons in primary visual cortex are selective for stimulus orientation, and a neuron's
preferred orientation changes little when the stimulus is switched from one eye to the other. It …

Comprehensive software suite for functional analysis and synaptic input mapping of dendritic spines imaged in vivo

Y Yu, LM Adsit, IT Smith - Neurophotonics, 2024 - spiedigitallibrary.org
Significance Advances in genetically encoded sensors and two-photon imaging have
unlocked functional imaging at the level of single dendritic spines. Synaptic activity can be …

Prediction of future input explains lateral connectivity in primary visual cortex

S Klavinskis-Whiting, E Fristed, Y Singer, MF Iacaruso… - bioRxiv, 2024 - biorxiv.org
Neurons in primary visual cortex (V1) show a remarkable functional specificity in their pre-
and postsynaptic partners. Recent work has revealed a variety of wiring biases describing …