Photoreceptor cells and RPE contribute to the development of diabetic retinopathy

D Tonade, TS Kern - Progress in retinal and eye research, 2021 - Elsevier
Diabetic retinopathy (DR) is a leading cause of blindness. It has long been regarded as
vascular disease, but work in the past years has shown abnormalities also in the neural …

[HTML][HTML] The mouse retina as an angiogenesis model

A Stahl, KM Connor, P Sapieha, J Chen… - … & visual science, 2010 - arvojournals.org
The mouse retina has been used extensively over the past decades to study both
physiologic and pathologic angiogenesis. Over time, various mouse retina models have …

Vascular endothelial growth factors and angiogenesis in eye disease

AN Witmer, G Vrensen, CJF Van Noorden… - Progress in retinal and …, 2003 - Elsevier
The vascular endothelial growth factor (VEGF) family of growth factors controls pathological
angiogenesis and increased vascular permeability in important eye diseases such as …

Significance of blood vessel leakiness in cancer

DM McDonald, P Baluk - 2002 - AACR
Despite major advances in the field of tumor angiogenesis, relatively little attention has been
paid to the permeability of blood vessels in tumors. The leakiness of tumor vessels is well …

[WITHDRAWN] retinal vasculature in development and diseases

Y Sun, LEH Smith - Annual review of vision science, 2018 - annualreviews.org
This article was withdrawn on October 15, 2020, at the request of the journal editors, with
agreement from the authors, owing to a substantial amount of unattributed or improperly …

Display technologies: application for the discovery of drug and gene delivery agents

A Sergeeva, MG Kolonin, JJ Molldrem… - Advanced drug delivery …, 2006 - Elsevier
Recognition of molecular diversity of cell surface proteomes in disease is essential for the
development of targeted therapies. Progress in targeted therapeutics requires establishing …

Hypoxia and oxidative stress in the causation of diabetic retinopathy

G B. Arden, S Sivaprasad - Current diabetes reviews, 2011 - benthamdirect.com
Diabetic retinopathy is associated with hyperglycemia, and there is convincing evidence that
oxidative stress (the overproduction of reactive oxygen species (ROS)) measured indirectly …

From oxygen to erythropoietin: relevance of hypoxia for retinal development, health and disease

C Caprara, C Grimm - Progress in retinal and eye research, 2012 - Elsevier
Photoreceptors and other cells of the retina consume large quantities of energy to efficiently
convert light information into a neuronal signal understandable by the brain. The necessary …

Dyslipidemia in retinal metabolic disorders

Z Fu, CT Chen, G Cagnone, E Heckel… - EMBO Molecular …, 2019 - embopress.org
The light‐sensitive photoreceptors in the retina are extremely metabolically demanding and
have the highest density of mitochondria of any cell in the body. Both physiological and …

Spare the rod and spoil the eye

GB Arden, RL Sidman, W Arap… - British journal of …, 2005 - bjo.bmj.com
This review presents a new unified view of the pathogenesis of three common causes of
acquired retinal degenerative disease—diabetic retinopathy, age related macular …