Interferon-gamma-and perforin-mediated immune responses for resistance against Toxoplasma gondii in the brain

Y Suzuki, Q Sa, M Gehman, E Ochiai - Expert reviews in molecular …, 2011 - cambridge.org
Toxoplasma gondii is an obligate intracellular protozoan parasite that causes various
diseases, including lymphadenitis, congenital infection of fetuses and life-threatening …

Host Resistance in the Brain against Toxoplasma gondii

Y Suzuki - The Journal of infectious diseases, 2002 - academic.oup.com
Abstract Interferon (IFN)-γ—dependent, cell-mediated immunity plays the major role in
resistance against development of toxoplasmic encephalitis (TE). Humoral immunity also …

Effect of Cytokines on Growth of Toxoplasma gondii in Murine Astrocytes

SK Halonen, FC Chiu, LM Weiss - Infection and immunity, 1998 - Am Soc Microbiol
Cytokines play a significant role in the regulation of Toxoplasma gondii in the central
nervous system. Cytokine-activated microglia are important host defense cells in central …

Immunopathogenesis of cerebral toxoplasmosis

Y Suzuki - The Journal of infectious diseases, 2002 - academic.oup.com
Interferon (IFN)-γ is an absolute requirement for resistance against acute acquired infection
with Toxoplasma gondii and development of toxoplasmic encephalitis (TE) during the late …

The role of astrocytes in the immunopathogenesis of toxoplasmic encephalitis

EH Wilson, CA Hunter - International journal for parasitology, 2004 - Elsevier
Challenge with the parasite Toxoplasma gondii eventually leads to persistent infection
characterised by the presence of tissue cysts in the brain of the host. In immunocompetent …

IL‐4 and IL‐13 regulate the induction of indoleamine 2,3‐dioxygenase activity and the control of Toxoplasma gondii replication in human fibroblasts activated with …

ACL Chaves, IP Ceravolo, JAS Gomes… - European journal of …, 2001 - Wiley Online Library
The ability of up‐regulatory [recombinant (r) IFN‐γ, rIFN‐β and rTNF‐α] and down‐regulatory
(rIL‐4, rIL‐10 and rIL‐13) cytokines to control the expression of indoleamine 2, 3 …

Autism spectrum disorders may be due to cerebral toxoplasmosis associated with chronic neuroinflammation causing persistent hypercytokinemia that resulted in an …

J Prandota - Research in Autism Spectrum Disorders, 2010 - Elsevier
Worldwide, approximately 2 billion people are chronically infected with Toxoplasma gondii
with largely yet unknown consequences. Patients with autism spectrum disorders (ASD) …

Stimulation of IL-1β and IL-6 through NF-κB and sonic hedgehog-dependent pathways in mouse astrocytes by excretory/secretory products of fifth-stage larval …

KY Chen, LC Wang - Parasites & vectors, 2017 - Springer
Background Angiostrongylus cantonensis is an important causative agent of eosinophilic
meningitis and eosinophilic meningoencephalitis in humans. Previous studies have shown …

Cytokines Involved in Toxoplasmic encephalitis

ME Sarciron, A Gherardi - Scandinavian Journal of …, 2000 - Wiley Online Library
Reactivation of cerebral toxoplasmosis occurs in approximately 30% of acquired immune
deficiency syndrome (AIDS) patients who are seropositive for Toxoplasma gondii and a …

Differential development of Toxoplasma gondii in neural cells

R Fagard, H Van Tan, C Creuzet, H Pelloux - Parasitology Today, 1999 - cell.com
Differential Development of Toxoplasma gondii in Neural Cells: Parasitology Today Skip to
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