Thermal ablation of biological tissues in disease treatment: A review of computational models and future directions

S Singh, R Melnik - Electromagnetic biology and medicine, 2020 - Taylor & Francis
Percutaneous thermal ablation has proven to be an effective modality for treating both
benign and malignant tumours in various tissues. Among these modalities, radiofrequency …

Distributed biological computation: from oscillators, logic gates and switches to a multicellular processor and neural computing applications

M Moškon, R Komac, N Zimic, M Mraz - Neural Computing and …, 2021 - Springer
Ever since its foundational years, synthetic biology has been focused on the implementation
of biological computing structures. In the beginning, engineered biological computation has …

Using optimal control to understand complex metabolic pathways

N Tsiantis, JR Banga - BMC bioinformatics, 2020 - Springer
Background Optimality principles have been used to explain the structure and behavior of
living matter at different levels of organization, from basic phenomena at the molecular level …

Global optimization approach for parameter estimation in stochastic dynamic models of biosystems

C Sequeiros, I Otero-Muras, C Vázquez… - … /ACM Transactions on …, 2022 - ieeexplore.ieee.org
Mechanistic dynamic models have become an essential tool for understanding biomolecular
networks and other biological systems. Biochemical stochasticity can be extremely important …

Spatially organizing biochemistry: choosing a strategy to translate synthetic biology to the factory

CM Jakobson, D Tullman-Ercek, NM Mangan - Scientific reports, 2018 - nature.com
Natural biochemical systems are ubiquitously organized both in space and time.
Engineering the spatial organization of biochemistry has emerged as a key theme of …

[PDF][PDF] Computational modelling of liver metabolism and its applications in research and the clinics

TC Tomaš, M Moškon, M Mraz, D Rozman - Acta Chim Slov, 2018 - academia.edu
Computational models of liver metabolism are gaining an increasing importance within the
research community. Moreover, their first clinical applications have been reported in recent …

Community‐scale models of microbiomes: Articulating metabolic modelling and metagenome sequencing

K Cerk, P Ugalde‐Salas, CG Nedjad… - Microbial …, 2024 - Wiley Online Library
Building models is essential for understanding the functions and dynamics of microbial
communities. Metabolic models built on genome‐scale metabolic network reconstructions …

[PDF][PDF] Mechanistic mathematical modeling of spatiotemporal microtubule dynamics and regulation in vivo

LA Widmer - 2018 - research-collection.ethz.ch
The microtubule cytoskeleton is a key component of eukaryotic life: during cell division it
forms the mitotic spindle, an apparatus that is responsible for faithfully segregating genetic …