Extracellular microvesicles/exosomes: discovery, disbelief, acceptance, and the future?

MZ Ratajczak, J Ratajczak - Leukemia, 2020 - nature.com
There are concepts in science that need time to overcome initial disbelief before finally
arriving at the moment when they are embraced by the research community. One of these …

Cell surface mechanics and the control of cell shape, tissue patterns and morphogenesis

T Lecuit, PF Lenne - Nature reviews Molecular cell biology, 2007 - nature.com
Embryonic morphogenesis requires the execution of complex mechanisms that regulate the
local behaviour of groups of cells. The orchestration of such mechanisms has been mainly …

Wnt signaling and stem cell control

R Nusse, C Fuerer, W Ching, K Harnish… - Cold Spring Harbor …, 2008 - symposium.cshlp.org
In many contexts, self-renewal and differentiation of stem cells are influenced by signals
from their environment, constituting a niche. It is postulated that stem cells compete for local …

Cell and molecular biology of Notch

UM Fiúza, AM Arias - Journal of Endocrinology, 2007 - joe.bioscientifica.com
Notch signalling is a cell–cell communication process, which allows the establishment of
patterns of gene expression and differentiation, regulates binary cell fate choice and the …

Genome-wide analysis of human kinases in clathrin-and caveolae/raft-mediated endocytosis

L Pelkmans, E Fava, H Grabner, M Hannus… - Nature, 2005 - nature.com
Endocytosis is a key cellular process, encompassing different entry routes and endocytic
compartments. To what extent endocytosis is subjected to high-order regulation by the …

Heterodimerization and endocytosis of Arabidopsis brassinosteroid receptors BRI1 and AtSERK3 (BAK1)

E Russinova, JW Borst, M Kwaaitaal… - The Plant …, 2004 - academic.oup.com
In Arabidopsis thaliana brassinosteroid (BR), perception is mediated by two Leu-rich repeat
receptor-like kinases, BRASSINOSTEROID INSENSITIVE1 (BRI1) and BRI1-ASSOCIATED …

[HTML][HTML] Mechanism of nodal flow: a conserved symmetry breaking event in left-right axis determination

Y Okada, S Takeda, Y Tanaka, JCI Belmonte… - Cell, 2005 - cell.com
The leftward flow in extraembryonic fluid is critical for the initial determination of the left-right
axis of mouse embryos. It is unclear if this is a conserved mechanism among other …

Endocytic regulation of TGF-β signaling

YG Chen - Cell research, 2009 - nature.com
Transforming growth factor-β (TGF-β) signaling is tightly regulated to ensure its proper
physiological functions in different cells and tissues. Like other cell surface receptors, TGF-β …

The Arabidopsis thaliana SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASES1 and 2 Control Male Sporogenesis

C Albrecht, E Russinova, V Hecht, E Baaijens… - The Plant …, 2005 - academic.oup.com
Abstract The Arabidopsis thaliana SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASE
(SERK) family of plasma membrane receptors consists of five closely related members. The …

Linking albinism and immunity: the secrets of secretory lysosomes

J Stinchcombe, G Bossi, GM Griffiths - Science, 2004 - science.org
Lysosomes are membrane-bound organelles that are found in all mammalian cells and
contain hydrolases and lipases required for protein and membrane degradation. In many …