Hepatitis E virus: advances and challenges

I Nimgaonkar, Q Ding, RE Schwartz… - Nature Reviews …, 2018 - nature.com
At least 20 million hepatitis E virus (HEV) infections occur annually, with> 3 million
symptomatic cases and∼ 60,000 fatalities. Hepatitis E is generally self-limiting, with a case …

[HTML][HTML] Zoonotic hepatitis E virus: classification, animal reservoirs and transmission routes

V Doceul, E Bagdassarian, A Demange, N Pavio - Viruses, 2016 - mdpi.com
During the past ten years, several new hepatitis E viruses (HEVs) have been identified in
various animal species. In parallel, the number of reports of autochthonous hepatitis E in …

Public health risks associated with hepatitis E virus (HEV) as a food‐borne pathogen

EFSA Panel on Biological Hazards (BIOHAZ)… - Efsa …, 2017 - Wiley Online Library
Hepatitis E virus (HEV) is an important infection in humans in EU/EEA countries, and over
the last 10 years more than 21,000 acute clinical cases with 28 fatalities have been notified …

Detection of a novel hepatitis E-like virus in faeces of wild rats using a nested broad-spectrum RT-PCR

R Johne, A Plenge-Bonig, M Hess… - Journal of General …, 2010 - microbiologyresearch.org
Hepatitis E is a rare human disease in developed countries. It is caused by hepatitis E virus
(HEV), which is probably transmitted zoonotically to humans from domestic pigs and wild …

From barnyard to food table: the omnipresence of hepatitis E virus and risk for zoonotic infection and food safety

XJ Meng - Virus research, 2011 - Elsevier
Hepatitis E virus (HEV) is an important but extremely understudied pathogen. The
mechanisms of HEV replication and pathogenesis are poorly understood, and a vaccine …

Hepatitis E virus infects neurons and brains

X Zhou, F Huang, L Xu, Z Lin… - The Journal of …, 2017 - academic.oup.com
Hepatitis E virus (HEV), as a hepatotropic virus, is supposed to exclusively infect the liver
and only cause hepatitis. However, a broad range of extrahepatic manifestations (in …

Molecular biology and replication of hepatitis E virus

D Cao, XJ Meng - Emerging microbes & infections, 2012 - Taylor & Francis
Hepatitis E virus (HEV), a single-stranded, positive-sense RNA virus, is responsible for acute
hepatitis E epidemics in many developing countries, and the virus is also endemic in some …

Hepeviridae: an expanding family of vertebrate viruses

R Johne, P Dremsek, J Reetz, G Heckel, M Hess… - Infection, Genetics and …, 2014 - Elsevier
The hepatitis E virus (HEV) was first identified in 1990, although hepatitis E-like diseases in
humans have been recorded for a long time dating back to the 18th century. The HEV …

[HTML][HTML] Orthohepevirus C: An Expanding Species of Emerging Hepatitis E Virus Variants

B Wang, D Harms, XL Yang, CT Bock - Pathogens, 2020 - mdpi.com
Hepatitis E virus (HEV) is an emerging zoonotic pathogen that has received an increasing
amount of attention from virologists, clinicians, veterinarians, and epidemiologists over the …

[HTML][HTML] Viral hepatitis E and chronicity: a growing public health concern

V Thakur, RK Ratho, S Kumar, SK Saxena… - Frontiers in …, 2020 - frontiersin.org
Hepatitis E viral infection recently emerges as a global health concern. Over the last decade,
the understanding of hepatitis E virus (HEV) had changed with the discovery of new …