[HTML][HTML] Radiotheranostics-precision medicine in nuclear medicine and molecular imaging

H Duan, A Iagaru, CM Aparici - Nanotheranostics, 2022 - ncbi.nlm.nih.gov
Abstract'See what you treat and treat what you see, at a molecular level', could be the motto
of theranostics. The concept implies diagnosis (imaging) and treatment of cells (usually …

Targeted palliative radionuclide therapy for metastatic bone pain

R Manafi-Farid, F Masoumi, G Divband, B Saidi… - Journal of clinical …, 2020 - mdpi.com
Bone metastasis develops in multiple malignancies with a wide range of incidence. The
presence of multiple bone metastases, leading to a multitude of complications and poorer …

Bone metastasis of breast cancer: molecular mechanisms and therapeutic strategies

L Pang, C Gan, J Xu, Y Jia, J Chai, R Huang, A Li, H Ge… - Cancers, 2022 - mdpi.com
Simple Summary In this review, we present knowledge of the molecular mechanisms and
therapeutic strategies of bone metastasis of breast cancer, particularly the interaction …

Photodynamic therapy and hyperthermia in combination treatment—Neglected forces in the fight against cancer

A Bienia, O Wiecheć-Cudak, AA Murzyn… - Pharmaceutics, 2021 - mdpi.com
Cancer is one of the leading causes of death in humans. Despite the progress in cancer
treatment, and an increase in the effectiveness of diagnostic methods, cancer is still highly …

The Curies' element: state of the art and perspectives on the use of radium in nuclear medicine

S Franchi, M Asti, V Di Marco, M Tosato - EJNMMI Radiopharmacy and …, 2023 - Springer
Background The alpha-emitter radium-223 (223Ra) is presently used in nuclear medicine
for the palliative treatment of bone metastases from castration-resistant prostate cancer. This …

Efficacy of a HER2-Targeted Thorium-227 Conjugate in a HER2-Positive Breast Cancer Bone Metastasis Model

J Karlsson, UB Hagemann, V Cruciani, CA Schatz… - Cancers, 2023 - mdpi.com
Simple Summary Human epidermal growth factor receptor 2 (HER2) is a protein present in
increased amounts in breast cancer compared with healthy breast tissue. Anti-cancer drugs …

Recent Advances in Emerging Radiopharmaceuticals and the Challenges in Radiochemistry and Analytical Chemistry

J Ding, S Qin, X Hou, J Zhang, M Yang, S Ma… - TrAC Trends in …, 2024 - Elsevier
Radiopharmaceuticals are of growing interests in the development of theranostic agents and
personalized medicine because of their unique advantages. Diagnosis (via molecular …

RADTHYR: an open-label, single-arm, prospective multicenter phase II trial of Radium-223 for the treatment of bone metastases from radioactive iodine refractory …

D Deandreis, A Maillard, S Zerdoud… - European Journal of …, 2021 - Springer
Purpose This is the first prospective trial evaluating the efficacy of alpha emitter Radium-223
in patients with bone metastases from radioactive iodine (RAI) refractory (RAIR) …

Radium-223 in women with hormone receptor-positive bone-metastatic breast cancer receiving endocrine therapy: pooled analysis of two international, phase 2 …

HS Rugo, CH Van Poznak, P Neven… - Breast Cancer Research …, 2024 - Springer
Background Most women with advanced breast cancer have skeletal metastases. Radium-
223 is an alpha-emitting radionuclide that selectively targets areas of bone metastases …

Bone Metastases

GJR Cook, MP Thorpe - The Cancer Journal, 2024 - journals.lww.com
Bone metastases occur frequently in common malignancies such as breast and prostate
cancer. They are responsible for considerable morbidity and skeletal-related events …