Mechanistic insights into the pharmacological significance of silymarin
Medicinal plants are considered the reservoir of diverse therapeutic agents and have been
traditionally employed worldwide to heal various ailments for several decades. Silymarin is a …
traditionally employed worldwide to heal various ailments for several decades. Silymarin is a …
Metal-phenolic networks for cancer theranostics
P Liu, X Shi, S Zhong, Y Peng, Y Qi, J Ding… - Biomaterials …, 2021 - pubs.rsc.org
Metal-phenolic networks (MPNs) have shown promising potential in biomedical applications
since they provide a rapid, simple and robust way to construct multifunctional nanoplatforms …
since they provide a rapid, simple and robust way to construct multifunctional nanoplatforms …
Dysbiosis and Alzheimer's disease: a role for chronic stress?
Alzheimer's disease (AD) is an incurable, neuropsychiatric, pathological condition that
deteriorates the worth of geriatric lives. AD is characterized by aggregated senile amyloid …
deteriorates the worth of geriatric lives. AD is characterized by aggregated senile amyloid …
Curcumin attenuated neurotoxicity in sporadic animal model of Alzheimer's disease
I ELBini-Dhouib, R Doghri, A Ellefi, I Degrach… - Molecules, 2021 - mdpi.com
Alzheimer's disease (AD) is one of the most common neurodegenerative diseases leading
to dementia. Despite research efforts, currently there are no effective pharmacotherapeutic …
to dementia. Despite research efforts, currently there are no effective pharmacotherapeutic …
Boron compounds exhibit protective effects against aluminum-induced neurotoxicity and genotoxicity: In vitro and in vivo study
Genetic, neuropathological and biochemical investigations have revealed meaningful
relationships between aluminum (Al) exposure and neurotoxic and hematotoxic damage …
relationships between aluminum (Al) exposure and neurotoxic and hematotoxic damage …
Pharmaceutical prospects of Silymarin for the treatment of neurological patients: an updated insight
Background Silymarin is a polyphenolic flavonoid complex extricated from dried fruits and
seeds of the plant Silybum marianum L. Chemically, it is a mixture of flavonolignan …
seeds of the plant Silybum marianum L. Chemically, it is a mixture of flavonolignan …
Oxidative Stress, Endoplasmic Reticulum Stress and Apoptosis in the Pathology of Alzheimer's Disease
BE Ekundayo, TO Obafemi, OB Adewale… - Cell Biochemistry and …, 2024 - Springer
Alzheimer's disease (AD) accounts for a major statistic among the class of
neurodegenerative diseases. A number of mechanisms have been identified in its …
neurodegenerative diseases. A number of mechanisms have been identified in its …
Evolving therapeutic interventions for the management and treatment of Alzheimer's disease
Alzheimer's Disease (AD) patients experience diverse symptoms, including memory loss,
cognitive impairment, behavioral abnormalities, mood changes, and mental issues. The …
cognitive impairment, behavioral abnormalities, mood changes, and mental issues. The …
Unlocking the possibilities of therapeutic potential of silymarin and silibinin against neurodegenerative diseases-a mechanistic overview
Silymarin, a bioflavonoid derived from the Silybum marianum plant, was discovered in 1960.
It contains C 25 and has been extensively used as a therapeutic agent against liver-related …
It contains C 25 and has been extensively used as a therapeutic agent against liver-related …
Endoplasmic reticulum stress and mitochondrial injury are critical molecular drivers of AlCl3-induced testicular and epididymal distortion and dysfunction: protective …
HA Khalaf, AZ Elsamanoudy, SM Abo-Elkhair… - Histochemistry and Cell …, 2022 - Springer
Aluminum, the third most plentiful metal in the Earth's crust, has potential for human
exposure and harm. Oxidative stress plays an essential role in producing male infertility by …
exposure and harm. Oxidative stress plays an essential role in producing male infertility by …