Molecular pathways of oestrogen receptors and β‐adrenergic receptors in cardiac cells: Recognition of their similarities, interactions and therapeutic value

JO Machuki, HY Zhang, SE Harding, H Sun - Acta Physiologica, 2018 - Wiley Online Library
Oestrogen receptors (ERs) and β‐adrenergic receptors (βARs) play important roles in the
cardiovascular system. Moreover, these receptors are expressed in cardiac myocytes and …

Current Targets and Future Directions of Positive Inotropes for Heart Failure

S Fairuz, CW Ang, F Mraiche… - Current Medicinal …, 2024 - benthamdirect.com
While a congestive heart failure patient will ultimately need an assist device or even a
replacement heart as the disease progresses, not every patient is qualified for such …

G-Protein-Coupled Estrogen Receptor Expression in Rat Uterine Artery Is Increased by Pregnancy and Induces Dilation in a Ca2+ and ERK1/2 Dependent Manner

T Tropea, D Rigiracciolo, M Esposito… - International Journal of …, 2022 - mdpi.com
Increasing levels of estrogens across gestation are partly responsible for the physiological
adaptations of the maternal vasculature to pregnancy. The G protein-coupled estrogen …

Evaluation of biological activity exerted by Dibenzo [b, e] Thiophene-11 (6H)-One on left ventricular pressure using an isolated rat heart model

L Figueroa-Valverde, M Rosas-Nexticapa… - Drug …, 2023 - thieme-connect.com
Background Some studies show that some Dibenzo derivatives can produce changes in the
cardiovascular system; however, its molecular mechanism is not very clear. Objective The …

GPER modulates tone and coronary vascular reactivity in male and female rats

AR Debortoli… - Journal of …, 2017 - jme.bioscientifica.com
Compared with age-matched men, premenopausal women are largely protected from
coronary artery disease, a difference that is lost after menopause. The effects of oestrogens …

Fatty acid oxidation and cardiovascular risk during menopause: a mitochondrial connection?

PJ Oliveira, RA Carvalho, P Portincasa… - Journal of …, 2012 - Wiley Online Library
Menopause is a consequence of the normal aging process in women. This fact implies that
the physiological and biochemical alterations resulting from menopause often blur with …

[HTML][HTML] Deficiency of sex hormones does not affect 17-ß-estradiol-induced coronary vasodilation in the isolated rat heart

RL Santos, JT Lima, WN Rouver… - Brazilian Journal of …, 2016 - SciELO Brasil
The relaxation of coronary arteries by estrogens in the coronary vascular beds of naive and
hypertensive rats has been well described. However, little is known about this action in …

[HTML][HTML] Endothelin-1 overexpression and endothelial nitric oxide synthase knock-out induce different pathological responses in the heart of male and female mice

N Vignon-Zellweger, K Relle, J Rahnenführer… - Life sciences, 2014 - Elsevier
Aims The nitric oxide and endothelin systems are key components of a local paracrine
hormone network in the heart. We previously reported that diastolic dysfunction observed in …

Expression and regulation of glucocorticoid-induced leucine zipper in the developing anterior pituitary gland

LE Ellestad, SA Malkiewicz, HD Guthrie… - Journal of …, 2009 - jme.bioscientifica.com
The role of the adipocyte-derived factor visfatin in metabolism remains controversial,
although some pancreatic β-cell-specific effects have been reported. This study investigated …

Biological Activity of a Coumarin Derivative on Heart Failure Using an Ischemia/Reperfusion Injury Model

L Figueroa-Valverde, M Rosas-Nexticapa… - Drug …, 2024 - thieme-connect.com
Heart failure is a health problem worldwide. There are some drugs for it, including digoxin,
spironolactone, captopril, and valsartan, but some of these drugs can produce secondary …